PHYSL 555 - Physiology of Lipids and Lipoproteins

3 units (fi 6)(EITHER, 3-0-0)

Faculty of Medicine and Dentistry

Advanced course focusing on specific aspects of the physiological regulation of lipid and lipoprotein metabolism. Topics include the transcriptional and post-translational mechanisms governing the synthesis and degradation of important enzymes, lipids, and lipid transport molecules; the role of lipid mediators in signaling pathways and protein modification; the assembly and dynamics of lipoproteins and biological membranes; genetic disruptions of lipid regulatory proteins such as cell surface receptors leading to human disease. Prerequisites: A minimum grade of B- in PHYSL 210 or 212/214 or consent of Department. Lectures are the same as for PHYSL 455, but with additional assignments and evaluation appropriate to graduate studies. This course may not be taken for credit if credit has already been obtained in PHYSL 455.