BIOCH 430 - Biochemistry of Eukaryotic Gene Expression

3 units (fi 6)(FIRST, 3-0-0)

This course focuses on the biochemical mechanisms underlying the regulation of gene expression in eukaryotic cells. The focus will be on the regulation of gene expression at the levels of transcription, post-transcriptional processing, and translation. The course will specifically address biochemical and structural mechanisms underlying gene regulation, as well as biochemical experimental methods that can be used to probe these activities. Prerequisites: BIOCH 320 and 330, both with a minimum grade of B- or consent of Department. This course is intended for students in Honors or Specialization in Biochemistry. Students in other programs may be admitted subject to availability and with the consent of the Department. Graduate students may not register for credit (see BIOCH 530).

BIOCH 530 - Biochemistry of Eukaryotic Gene Expression

3 units (fi 6)(EITHER, 3-0-0)

This course focuses on the biochemical mechanisms underlying the regulation of gene expression in eukaryotic cells. The focus will be on the regulation of gene expression at the levels of transcription, post-transcriptional processing, and translation. The course will specifically address biochemical and structural mechanisms underlying gene regulation, as well as biochemical experimental methods that can be used to probe these activities. Prerequisites: BIOCH 320 and 330 with a minimum grade of B- or consent of Department. Lectures are the same as for BIOCH 430, but with additional assignments and evaluation appropriate to graduate studies. Students in other programs may be admitted subject to availability and with the consent of the Department. This course may not be taken for credit if credit has already been obtained in BIOCH 430.

BIOCH 623A - Special Topics in Research on Polynucleotides

1 unit (fi 4)(TWO TERM, 0-1S-0)

This course is a journal club and discussion group in which current research topics on nucleic acids, molecular and cellular biology are discussed. Specific subjects presented range from biochemistry, genetics and microbiology to developmental biology and clinical aspects of nucleic acid derived therapeutics.

BIOCH 626A - Special Topics in Protein Research

1 unit (fi 4)(TWO TERM, 0-1S-0)

Seminar course for advanced students. Detailed consideration is given to recent advances in research on protein structure and function and mechanism of enzyme action. Prerequisite: BIOCH 420 or consent of Department.

BIOCH 330 - Nucleic Acids and Molecular Biology

3 units (fi 6)(EITHER, 3-0-0)

This course is designed to provide students with a comprehensive introduction to the biochemistry of nucleic acids. It covers: the structure and properties of nucleotides and nucleic acids; DNA-based information technologies; genes and chromosome structure; molecular mechanisms in DNA replication, repair, and recombination; RNA metabolism; protein synthesis and targeting; the regulation of gene expression. Prerequisites: BIOCH 200, CHEM 102 (or SCI 100), and CHEM 263, with a minimum GPA of 2.70 for these three courses. In the case of over-subscription, preference will be given to students enrolled in programs with a requirement for this course.

BIOCH 623B - Special Topics in Research on Polynucleotides

1 unit (fi 4)(TWO TERM, 0-1S-0)

This course is a journal club and discussion group in which current research topics on nucleic acids, molecular and cellular biology are discussed. Specific subjects presented range from biochemistry, genetics and microbiology to developmental biology and clinical aspects of nucleic acid derived therapeutics.

BIOCH 626B - Special Topics in Protein Research

1 unit (fi 4)(TWO TERM, 0-1S-0)

Seminar course for advanced students. Detailed consideration is given to recent advances in research on protein structure and function and mechanism of enzyme action. Prerequisite: BIOCH 420 or consent of Department.