BIOCH 441 - Structure and Function of Biological Membranes

3 units (fi 6)(FIRST, 3-0-0)

Survey of the structure and function of biological membranes. Topics include the structure, properties and composition of biomembranes, characterization and structural principles of membrane lipids and proteins, lateral and transverse asymmetry, dynamics, lipid-protein interactions, membrane enzymology, permeability, and biogenesis. Prerequisites: BIOCH 320, with a minimum grade of B- or consent of Department. This course is intended for students in Honors or Specialization in Biochemistry. Students in other programs may be admitted subject to availability and with the consent of the Department. Graduate students may not register for credit (see BIOCH 541).

BIOCH 541 - Structure and Function of Biological Membranes

3 units (fi 6)(EITHER, 3-0-0)

Survey of the structure and function of biological membranes. Topics include the structure, properties and composition of biomembranes, characterization and structural principles of membrane lipids and proteins, lateral and transverse asymmetry, dynamics, lipid-protein interactions, membrane enzymology, permeability, and biogenesis. Prerequisites: BIOCH 320 or equivalent, with a minimum grade of B- or consent of Department. Lectures are the same as for BIOCH 441, but with additional assignments and evaluation appropriate to graduate studies. Students in other programs may be admitted subject to availability and with the consent of the Department. This course may not be taken for credit if credit has already been obtained in BIOCH 441.

BIOCH 465 - Methods in Molecular Biophysics

3 units (fi 6)(SECOND, 3-0-0)

Survey of biophysical methods used in the characterization and structural determination of biological macromolecules, from ensemble measurements to single-molecule detection. Topics include mass spectrometry, optical spectroscopy, light microscopy, X-ray and neutron diffraction, electron microscopy, molecular dynamics and nuclear magnetic resonance. Emphasis is on using techniques in evaluating structure-function relationships through the discussion of representative macromolecular systems. Prerequisites: BIOCH 320 with a minimum grade of B- or consent of the Department. This course is intended for students in Honors or Specialization in Biochemistry. Students in other programs may be admitted subject to availability and with the consent of the Department. This course cannot be taken for credit if credit has already been obtained in BIOCH 460.

BIOCH 565 - Methods in Molecular Biophysics

3 units (fi 6)(EITHER, 3-0-0)

Survey of biophysical methods used in the characterization and structural determination of biological macromolecules, from ensemble measurements to single-molecule detection. Topics include mass spectrometry, optical spectroscopy, light microscopy, X-ray and neutron diffraction, electron microscopy, molecular dynamics and nuclear magnetic resonance. Emphasis is on using techniques in evaluating structure-function relationships through the discussion of representative macromolecular systems. Lectures are the same as for BIOCH 465, but with additional assignments and evaluation appropriate to graduate studies. This course cannot be taken for credit if credit has already been obtained in BIOCH 460 or 465.

BIOCH 620 - Selected Topics in Protein Structure, Function, and Regulation

3 units (fi 6)(SECOND, 0-3S-0)

Directed reading and seminar course, based on papers taken from recent literature of protein research. Students critically discuss the papers and give oral presentations to the class. Designed for graduate students. Prerequisite: BIOCH 420 or equivalent, or consent of Department.