BIOCH 481 - Design and Construction of Synthetic Biological Systems I

3 units (fi 6)(FIRST, 3-0-0)

This course explores both the opportunities and challenges of synthetic life by providing a practical and theoretical introduction to this new discipline through lectures, class discussion, and hands on computational exercises. Topics covered include: natural vs artificial design of genetic circuits, and the theoretical aspects of gene and gene network construction using molecular biology techniques. Prerequisites: BIOCH 330 (or equivalent), registration in the Faculties of Science or Engineering, and a minimum GPA 3.3 (or consent of the department).

BIOCH 425 - Proteomics

3 units (fi 6)(EITHER, 3-0-1/2)

An advanced course focusing on the analysis of protein function and protein-protein interactions within the context of the entire protein complement of a cell. Some aspects of protein structure as it pertains to the principles of protein-protein interactions will be covered along with genetic and biochemical methods for the analysis of protein complexes, protein interaction networks and system wide protein identification and dynamics. This course is intended for students in Honors or Specialization in Biochemistry. Students in other programs may be admitted subject to availability and with the consent of the Department. Prerequisites: BIOCH 320 and BIOCH 330 with a minimum GPA of 3.0 in these courses.

BIOCH 482 - Design and Construction of Synthetic Biological Systems II

3 units (fi 6)(SECOND, 0-0-4)

This course expands on BIOCH 481, providing opportunity for further skill development in analysis of the function of natural and engineered gene and metabolic networks. These computational labs are intended to explore the concepts applied in computer modeling during the design, testing, and optimization steps required to create biological model systems. Prerequisites: BIOCH 481.

BIOCH 525 - Proteomics

3 units (fi 6)(EITHER, 3-0-1/2)

An advanced course focusing on the analysis of protein function and protein-protein interactions within the context of the entire protein complement of a cell. Some aspects of protein structure as it pertains to the principles of protein-protein interactions will be covered along with genetic and biochemical methods for the analysis of protein complexes, protein interaction networks and system wide protein identification and dynamics. This course is intended for students in Biochemistry but students in other programs may be admitted subject to availability and with the consent of the Department. Prerequisites: BIOCH 420 and BIOCH 430 or their equivalent with a minimum GPA of 3.2 in these courses.