NEURO 411 - Clinical and Basic Science Aspects of Age-related Neurodegenerative Disorders

★ 3 (fi 6)(SECOND, 3-0-0)

Designed to provide senior undergraduate students in the Neuroscience program a comprehensive overview on neurobiology of various neurodegenerative disorders. Both clinical and basic science aspects of major neurodegenerative disorders such as Alzheimer's disease, Parkinson's disease, Huntington disease, Prion disease, Motor neuron disease (MND), Frontotemporal Dementia, Multiple Sclerosis and Chronic Traumatic Encephalopathy will be covered. We also intend to include a video presentation of patients with neurodegenerative disorders to outline major clinical and psychological features. In addition, papers on the most recent developments in the field of aging research have been integrated into the course. Prerequisites: NEURO 375 or PMCOL 371 or ZOOL 342 or consent from course coordinator. Credit may be obtained for either NEURO 411 or 511 but not both.

NEURO 511 - Clinical and Basic Science Aspects of Age-related Neurodegenerative Disorders

★ 3 (fi 6)(SECOND, 3-0-0)

Designed to provide graduate students in the Neuroscience program a comprehensive overview on neurobiology of various neurodegenerative disorders. Both clinical and basic science aspects of major neurodegenerative disorders such as Alzheimer's disease, Parkinson's disease, Huntington disease, Prion disease, Motor neuron disease (MND), Frontotemporal Dementia, Multiple Sclerosis and Chronic Traumatic Encephalopathy will be covered. We also intend to include a video presentation of patients with neurodegenerative disorders to outline major clinical and psychological features. In addition, papers on the most recent developments in the field of aging research have been integrated into the course. Prerequisites: NEURO 375 or PMCOL 371 or ZOOL 342 or consent from course coordinator. Credit may be obtained for either NEURO 411 or 511 but not both.

BIOCH 430 - Biochemistry of Eukaryotic Gene Expression

★ 3 (fi 6)(EITHER, 3-0-0)

This course focuses on the biochemical mechanisms underlying the regulation of gene expression in eukaryotic cells. The focus will be on the regulation of gene expression at the levels of transcription, post-transcriptional processing, and translation. The course will specifically address biochemical and structural mechanisms underlying gene regulation, as well as biochemical experimental methods that can be used to probe these activities. Prerequisites: BIOCH 320 and 330, both with a minimum grade of B- or consent of Department. This course is intended for students in Honors or Specialization in Biochemistry. Students in other programs may be admitted subject to availability and with the consent of the Department. Graduate students may not register for credit (see BIOCH 530).

BIOCH 530 - Biochemistry of Eukaryotic Gene Expression

★ 3 (fi 6)(EITHER, 3-0-0)

This course focuses on the biochemical mechanisms underlying the regulation of gene expression in eukaryotic cells. The focus will be on the regulation of gene expression at the levels of transcription, post-transcriptional processing, and translation. The course will specifically address biochemical and structural mechanisms underlying gene regulation, as well as biochemical experimental methods that can be used to probe these activities. Prerequisites: BIOCH 320 and 330 with a minimum grade of B- or consent of Department. Lectures are the same as for BIOCH 430, but with additional assignments and evaluation appropriate to graduate studies. Students in other programs may be admitted subject to availability and with the consent of the Department. This course may not be taken for credit if credit has already been obtained in BIOCH 430.

NEURO 410 - Cellular and Molecular Aspects of Normal Aging and Neurodegenerative Disorders

★ 3 (fi 6)(FIRST, 3-0-0)

Designed to provide senior undergraduate students in the Neuroscience program a comprehensive overview on neurobiology of normal aging and the cellular/molecular phenomena that may underlie various age-related neurodegenerative diseases. Aspects of neuronal and glial changes during the normal aging process will be covered. We also intend to include a video presentation of patients with neurodegenerative disorders to outline the impact of cellular/molecular changes on major clinical and psychological features. In addition, papers on the most recent developments in the field of aging research have been integrated into the course. Prerequisites: NEURO 375 or PMCOL 371 or ZOOL 342 or consent from course coordinator. Credit may be obtained for either NEURO 410 or 510 but not both.

NEURO 510 - Cellular and Molecular Aspects of Normal Aging and Neurodegenerative Disorders

★ 3 (fi 6)(FIRST, 3-0-0)

Designed to provide graduate students in the Neuroscience program a comprehensive overview of the neurobiology of normal aging and the cellular/molecular phenomena that may underlie various age-related neurodegenerative diseases. Aspects of neuronal and glial changes during the normal aging process will be covered. We also intend to include a video presentation of patients with neurodegenerative disorders to outline the impact of cellular/molecular changes on major clinical and psychological features. In addition, papers on the most recent developments in the field of aging research have been integrated into the course. Prerequisites: NEURO 375 or PMCOL 371 or ZOOL 342 or consent from course coordinator. Credit may be obtained for either NEURO 410 or 510 but not both.