BIOCH 430 - Biochemistry of Eukaryotic Gene Expression

3 units (fi 6)(FIRST, 3-0-0)

This course focuses on the biochemical mechanisms underlying the regulation of gene expression in eukaryotic cells. The focus will be on the regulation of gene expression at the levels of transcription, post-transcriptional processing, and translation. The course will specifically address biochemical and structural mechanisms underlying gene regulation, as well as biochemical experimental methods that can be used to probe these activities. Prerequisites: BIOCH 320 and BIOCH 330, both with a minimum grade of C+ or consent of the Department. This course is intended for students in Honors, Specialization and Majors in Biochemistry. Students in other programs may be admitted subject to availability and with the consent of the Department. Graduate students may not register for credit (see BIOCH 530).

BIOCH 530 - Biochemistry of Eukaryotic Gene Expression

3 units (fi 6)(FIRST, 3-0-0)

This course focuses on the biochemical mechanisms underlying the regulation of gene expression in eukaryotic cells. The focus will be on the regulation of gene expression at the levels of transcription, post-transcriptional processing, and translation. The course will specifically address biochemical and structural mechanisms underlying gene regulation, as well as biochemical experimental methods that can be used to probe these activities. Prerequisites: BIOCH 320 and BIOCH 330 with a minimum grade of C+ or consent of Department. Lectures are the same as for BIOCH 430, but with additional assignments and evaluation appropriate to graduate studies. Students in other programs may be admitted subject to availability and with the consent of the Department. This course may not be taken for credit if credit has already been obtained in BIOCH 430.

NEURO 410 - Cellular and Molecular Aspects of Normal Aging and Neurodegenerative Disorders

3 units (fi 6)(FIRST, 3-0-0)

Designed to provide senior undergraduate students in the Neuroscience program a comprehensive overview on neurobiology of normal aging and the cellular/molecular phenomena that may underlie various age-related neurodegenerative diseases. Aspects of neuronal and glial changes during the normal aging process will be covered. Common experimental models and techniques applied to the study of brain aging and neurodegeneration are introduced. Papers on the most recent developments in the field of aging research have been integrated into the course. Prerequisites: NEURO 371 or NEURO 375 or PHYSL 371 or ZOOL 342 or consent from the course coordinator. Credit may be obtained for either NEURO 410 or NEURO 510 but not both.

NEURO 510 - Cellular and Molecular Aspects of Normal Aging and Neurodegenerative Disorders

3 units (fi 6)(FIRST, 3-0-0)

Designed to provide graduate students in the Neuroscience program a comprehensive overview of the neurobiology of normal aging and the cellular/molecular phenomena that may underlie various age-related neurodegenerative diseases. Aspects of neuronal and glial changes during the normal aging process will be covered. Common experimental models and techniques applied to the study of brain aging and neurodegeneration are introduced. Papers on the most recent developments in the field of aging research have been integrated into the course. Prerequisite: Consent of course coordinator. Graduate students are expected to have completed a senior-level (typically third-year or higher) university course in cellular or molecular neuroscience. NEURO 371 or NEURO 375 or PHYSL 371 or ZOOL 342. Credit may be obtained for either NEURO 410 or NEURO 510 but not both.