BIOCH 420 - Proteins: Structure, Function, and Regulation

3 units (fi 6)(EITHER, 3-0-0)

Principles of protein structure, function, and dynamics, with an introduction to force fields used in modern molecular dynamics. Focus topics include an introduction to intrinsically disordered proteins and their role in misfolding diseases, the structural biology, ligand binding, and mechanisms of membrane bound enzymes, and mechanisms underlying the regulation of protein function and enzymes involved in cell signaling. Prerequisites: BIOCH 320, with a minimum grade of B- or consent of Department. This course is intended for students in Honors or Specialization in Biochemistry. Students in other programs may be admitted subject to availability and with the consent of the Department. Graduate students may not register for credit (see BIOCH 520).

BIOCH 498 - Directed Research Project

3 units (fi 6)(EITHER, 0-0-8)

Supervised research within a laboratory in the Department of Biochemistry, to be carried out over one term (Fall or Winter). The results of the research project will be presented in a short seminar. This course is intended for senior students in Honors or Specialization in Biochemistry. Students in other programs may be admitted subject to availability and background. This course is not a substitute for required courses in Biochemistry. Requires consent of the Department.

BIOCH 499A - Directed Research Project

3 units (fi 12)(TWO TERM, 0-0-8)

Supervised research within a laboratory in the Department of Biochemistry, to be carried out over both terms of Fall/Winter. The results of the research project will be presented in a final written report and an oral presentation. This course is required for the Honors program, but can be taken as a science elective by students in the Specialization program. Students in other programs may be admitted subject to availability. Prerequisites: BIOCH 401 and consent of the Department.

BIOCH 520 - Protein Chemistry, Structure, and Function

3 units (fi 6)(EITHER, 3-0-0)

Principles of protein structure, function, and dynamics, with an introduction to force fields used in modern molecular dynamics. Focus topics include an introduction to intrinsically disordered proteins and their role in misfolding diseases, the structural biology, ligand binding, and mechanisms of membrane bound enzymes, and mechanisms underlying the regulation of protein function and enzymes involved in cell signaling. Prerequisites: BIOCH 320, with a minimum grade of B- or consent of Department. Lectures are the same as for BIOCH 420, but with additional assignments and evaluation appropriate to graduate studies. Students in other programs may be admitted subject to availability and with the consent of the Department This course may not be taken for credit if credit has already been obtained in BIOCH 420.

BIOCH 498 - Directed Research Project

3 units (fi 6)(EITHER, 0-0-8)

Supervised research within a laboratory in the Department of Biochemistry, to be carried out over one term (Fall or Winter). The results of the research project will be presented in a short seminar. This course is intended for senior students in Honors or Specialization in Biochemistry. Students in other programs may be admitted subject to availability and background. This course is not a substitute for required courses in Biochemistry. Requires consent of the Department.

BIOCH 499B - Directed Research Project

3 units (fi 12)(TWO TERM, 0-0-8)

Supervised research within a laboratory in the Department of Biochemistry, to be carried out over both terms of Fall/Winter. The results of the research project will be presented in a final written report and an oral presentation. This course is required for the Honors program, but can be taken as a science elective by students in the Specialization program. Students in other programs may be admitted subject to availability. Prerequisites: BIOCH 401 and consent of the Department.

BIOCH 620 - Selected Topics in Protein Structure, Function, and Regulation

3 units (fi 6)(SECOND, 0-3S-0)

Directed reading and seminar course, based on papers taken from recent literature of protein research. Students critically discuss the papers and give oral presentations to the class. Designed for graduate students. Prerequisite: BIOCH 420 or equivalent, or consent of Department.