PMCOL 306 - Drug Disposition and Metabolism

3 units (fi 6)(EITHER, 3-0-0)

Faculty of Medicine and Dentistry

Study of factors that affect drug absorption, distribution, metabolism, and elimination (ADME). This includes an introduction to genetic factors that influence ADME of drugs, as well as practical exercises to illustrate pharmacokinetic principles and their relevance to therapeutic dosing. Drug-drug interactions and food-drug interactions will also be discussed. Prerequisites: PMCOL 200, BIOCH 200, PHYSL 210, or 212 and 214, or consent of Department. In the case of over-subscription, preference will be given to students enrolled in Pharmacology BSc degree programs.