PMCOL - Pharmacology

Offered By:
Faculty of Medicine and Dentistry
Faculty of Science

Below are the courses available from the PMCOL subject code. Select a course to view the available classes, additional class notes, class times, and textbooks.

PMCOL 200 - Drugs - An Introduction to Pharmacology View Available Classes

★ 3 (fi 6)(EITHER, 3-0-0)

Using examples of commonly used drugs (both therapeutic and illicit), we will explore what drugs do to the human body and in turn, what the body does to drugs. Recommended for students with an interest in pursuing medical science degrees and programs. Prerequisites: CHEM 101 and BIOL 107 or equivalent. Open to 2nd and 3rd year students only.


PMCOL 300 - Introduction to Pharmacology View Available Classes

★ 2 (fi 4)(FIRST, 28 HOURS)

Lecture topics present principles of pharmacology including practical application of commonly used drugs to the treatment of disease. This course is available only to students registered in the Bachelor of Science (Dental Hygiene) program.


PMCOL 301 - Introduction to Research in Pharmacology View Available Classes

★ 3 (fi 6)(FIRST, 0-0-8)

This course is designed to introduce students to pharmacological research. The project is carried out in a laboratory under the supervision of a member of the Department of Pharmacology. Laboratory projects may involve current topics and methodologies in diverse areas of Cardiovascular, Diabetes, Neuroscience or Molecular Pharmacology. Completion of this course requires a written report of the project and an oral presentation to an examining committee. Restricted to Pharmacology Honors or Specialization students in the third year of their program. There may be a limited number of spaces available. This course can also be taken as a six week Spring/Summer session course. Please contact the course coordinator for registration in the course.


PMCOL 302 - Introduction to Research in Pharmacology View Available Classes

★ 3 (fi 6)(SECOND, 0-0-8)

This course is designed to introduce students to pharmacological research. The project is carried out in a laboratory under the supervision of a member of the Department of Pharmacology. Laboratory projects may involve current topics and methodologies in diverse areas of Cardiovascular, Diabetes, Neuroscience or Molecular Pharmacology. Completion of this course requires a written report of the project and an oral presentation to an examining committee. Restricted to Pharmacology Honors or Specialization students in the third year of their program. There may be a limited number of spaces available. This course can also be taken as a six week Spring/Summer session course. Please contact the course coordinator for registration in the course.


PMCOL 303 - Introduction to Toxicology View Available Classes

★ 3 (fi 6)(EITHER, 3-0-0)

The adverse effects of xenobiotics on biological systems are discussed. Principles of toxicology are introduced. Responses of target organs to selected toxicants are described, with emphasis on molecular mechanisms. Special topics include chemical carcinogenesis, nanotoxicology, and endocrine disruptors. Prerequisites: PMCOL 200, BIOCH 200, PHYSL 210, or 212 and 214, or consent of Department.


PMCOL 305 - An Introduction to the Pharmacology of Drug Abuse View Available Classes

★ 3 (fi 6)(EITHER, 3-0-0)

An introduction to the complexities of drug abuse and the drugs of abuse. The student will be introduced to the psychological and social problems of drug abuse and their impact upon the abuser. Objectives of the course are to develop an understanding of addiction and a detailed knowledge of the nature of the commonly abused substances. Emphasis will be placed upon the pharmacology of drugs of abuse. Prerequisites: one of the following BIOCH 200, BIOL 201, CELL 201, PHYSL 210, PHSYL 212 and 214, PMCOL 200, PSYCO 275, ZOOL 241 and 242.


PMCOL 337 - Experimental Procedures in Pharmacology View Available Classes

★ 3 (fi 6)(EITHER, 0-0-6)

Provides a hands-on experience in addressing basic pharmacological questions. The course will employ both in vitro techniques and behavioural models. Emphasis will be placed on experimental design and data collection, analysis and presentation. Normally restricted to third year Pharmacology Specialization or Honors students. Students not in these programs may be admitted via consent of the instructor if space is available.


PMCOL 343 - Scientific Basis of Pharmacology: Part I View Available Classes

★ 3 (fi 6)(FIRST, 3-0-0)

This course, together with the subsequent PMCOL 344, provides a comprehensive study of the modern science of pharmacology. The objective of the course is to study how drugs act on physiological systems with an emphasis on therapeutic applications. This course may be especially useful to those students who wish to pursue a career in health sciences. Prerequisite: a 200-level PMCOL course or consent of instructor. Pre or corequisite: PHYSL 210, or 212 and 214, or consent of instructor. In the case of over subscription, preference will be given to students in the Pharmacology Specialization or Honors Programs.


PMCOL 344 - Scientific Basis of Pharmacology: Part II View Available Classes

★ 3 (fi 6)(SECOND, 3-0-0)

A continuation of PMCOL 343, this course will examine the therapeutic application of a variety of drugs and the mechanism(s) by which they affect physiological systems. Pre or co-requisite: PHYSL 210, or 212 and 214, or consent of instructor. In the case of over subscription, preference will be given to students in the Pharmacology Specialization or Honors Programs.


PMCOL 371 - Cellular Neuroscience View Available Classes

★ 3 (fi 6)(FIRST, 3-0-0)

Lectures presented by the Faculty of Medicine and Dentistry and the Faculty of Science on nerve cell membranes, ion channels, neurotransmitters and their receptors, synaptic mechanisms and plasticity, gene regulation and development, the physiology of small neural networks and disorders involving basic mechanisms. Prerequisite: PHYSL 210, or 212 and 214, or 252, or ZOOL 242. Students who have taken ZOOL 342 may not receive credit in PMCOL 371.


PMCOL 401 - Pharmacology Tutorial View Available Classes

★ 3 (fi 6)(FIRST, 0-0-8)

Independent research course. Hands-on experience is seen as a valuable asset for students graduating from BSc programs. With this in mind, this course provides an opportunity to work with a Faculty member on a research project during the Fall semester. The student and supervisor will mutually agree upon the details of the project. This is an excellent opportunity to learn current laboratory techniques, data analysis, laboratory notebook maintenance and presentation skills. Literature-based projects may also be available in which the student will be required to identify a research question and meet with the supervisor at regular intervals for discussion and guidance on preparation of a term paper and poster presentation. Prerequisites: PMCOL 343 and 344. Available only to students in the Pharmacology Specialization program or students who are granted consent by the Department of Pharmacology.


PMCOL 402 - Pharmacology Tutorial View Available Classes

★ 3 (fi 6)(SECOND, 0-0-8)

Independent research course. Hands-on experience is seen as a valuable asset for students graduating from BSc programs . With this in mind, this course provides an opportunity to work with a Faculty member on a research project during the Winter semester. The student and supervisor will mutually agree upon the details of the project. This is an excellent opportunity to learn current laboratory techniques, data analysis, laboratory notebook maintenance and presentation skills. Literature-based projects may also be available in which the student will be required to identify a research question and meet with the supervisor at regular intervals for discussion and guidance on preparation of a term paper and poster presentation. Prerequisites: PMCOL 343 and 344. Available only to students in the Pharmacology Specialization program or students who are granted consent by the Department of Pharmacology.


PMCOL 403 - Advanced Topics in Pharmacology View Available Classes

★ 3 (fi 6)(EITHER, 1-3S-1)

This course is designed to allow students to explore current topics and issues in pharmacology via projects such as literature reviews, systematic reviews, and community outreach and service. Under the guidance of a Faculty member, students will be expected to explore the current literature surrounding their topic of interest and will also be provided with selected readings by the supervisor. Prerequisites: PMCOL 303, PMCOL 305, PMCOL 343, PMCOL 344 or consent of instructor. This course will normally be restricted to students in the Pharmacology Specialization or Honors Programs. Students should consult the Department regarding the availability of projects.


PMCOL 404 - Core Principles in Pharmacology View Available Classes

★ 3 (fi 6)(EITHER, 3-0-0)

Topics will include the drug discovery process, advanced concepts in pharmacodynamics and pharmacokinetics, the use of animal models of disease by the pharmaceutical industry, and therapeutic drug monitoring. Prerequisites: PMCOL 343 and PMCOL 344. In the case of over subscription, preference will be given to students in the Pharmacology Specialization or Honors Programs.


PMCOL 412 - Drugs and the Nervous System View Available Classes

★ 3 (fi 6)(EITHER, 3-0-0)

The goal of PMCOL 412 is to learn about the molecular basis of disorders of the nervous system, current therapies in use, as well as novel potential treatments that are in clinical trials or at the preclinical experimental stage. Research frontiers in pain and neurodegenerative disorders such as Alzheimer, Parkinson and Huntington's disease, amyotrophic lateral sclerosis and multiple sclerosis among others, will be explored. Novel therapeutic targets and the potential treatments of tomorrow will be discussed. Prerequisites: PMCOL 343 and 344 or 371 or ZOOL 342 or consent of instructor.


PMCOL 415 - Cardiovascular Pharmacology View Available Classes

★ 3 (fi 6)(EITHER, 3-0-0)

Critical discussion and analysis of current research papers in cardiovascular pharmacology, grouped into themes. Recent developments and use of the literature will be emphasized. In-class participation during roundtable discussion to critique assigned papers is essential. Each theme will be accompanied by the student's written analyses of papers assigned but not discussed in class, in the format of a condensation/critique. Prerequisites: PMCOL 343 and 344. In cases of limited space, preference will be given to students in the Pharmacology program.


PMCOL 416 - Current Topics in Endocrine Pharmacology View Available Classes

★ 3 (fi 6)(EITHER, 3-0-0)

This course examines in detail, drugs (including natural hormones) that are used for treatment of endocrine diseases (e.g. diabetes, infertility, and growth deficiency). The focus of the course is the action of drugs on hormone receptors and on the regulation of hormone synthesis and secretion. Prerequisite: PMCOL 343 or 344 or consent of instructor.


PMCOL 425 - Problem Solving in Pharmacology and Therapeutics View Available Classes

★ 3 (fi 6)(EITHER, 3-0-0)

Students will be presented with problem cases involving patients with conditions, possibly needing drug therapy. They will identify the issues needing resolution, work collectively to find information to resolve them, and present these and their application to each patient to the group. The group will work to resolve outstanding issues after the presentations. Intended for senior undergraduate students. Prerequisites: PMCOL 343 and 344 and consent of Instructor.


PMCOL 450 - Diabetes and Its Pharmacotherapy View Available Classes

★ 3 (fi 6)(EITHER, 3-0-0)

This course will provide an overview of the current understanding of blood glucose homeostasis, insulin secretion and action, the actions of other important blood sugar-regulating hormones and the pathology of diabetes. Current pharmacological approaches for lowering blood glucose will be discussed, as will the latest experimental approaches in identifying potential drug targets and new treatments for diabetes. At the end of the course, students should have an appreciation for the mechanisms that control glucose homeostasis in health and diabetes, the diversity of drug targets and mechanisms by which diabetes drugs promote glucose control, and current rationale and lines of research leading to potential new treatments. Prerequisites: PMCOL 343 and 344 or consent of instructor.


PMCOL 475 - Signal Transduction Systems as Pharmacological Targets View Available Classes

★ 3 (fi 6)(EITHER, 3-0-0)

Regulation of various aspects of cell regulation, including proliferation, differentiation, metabolism, survival, motility, and gene transcription takes place via an array of well-organized signal transduction pathways. This course will cover topics related to the investigation of cellular transduction systems, and how pharmacological manipulation of these signaling pathways may be useful in the treatment of a diverse range of neurologic, neurodegenerative, inflammatory, immune, and metabolic diseases .Prerequisites: PMCOL 343 and 344 or PMCOL 371 or ZOOL 342 or consent of the instructor.


PMCOL 498B - Pharmacology Research Program View Available Classes

★ 3 (fi 12)(TWO TERM, 0-0-8)

During their fourth year all Honors candidates are required to carry out a program of directed research under the supervision of a staff member. This program will be related to the special interest of the student and will involve experimental work as well as two presentations and a written report on the part of the student. Students are encouraged to make arrangements with a supervisor of their choice before the fall term begins. Prerequisite: consent of Department. Normally available to fourth-year Honors students only.


PMCOL 501 - Pharmacology Tutorial, Research, and Reading Course View Available Classes

★ 3 (fi 6)(FIRST, 3-0-0)

This course is similar to PMCOL 401 except that the course material and student performance will be at a level suitable for graduate students.


PMCOL 502 - Pharmacology Tutorial, Research, and Reading Course View Available Classes

★ 3 (fi 6)(SECOND, 3-0-0)

This course is similar to PMCOL 401 except that the course material and student performance will be at a level suitable for graduate students.


PMCOL 508 - Molecular Pharmacology View Available Classes

★ 3 (fi 6)(EITHER, 3-0-0)

This course aims to provide an understanding of the general mechanisms of drug action at the molecular level. Theoretical aspects of drug-receptor interaction are presented in detail followed by a consideration of the mechanisms of signal transduction that have been associated with different receptor types. Prerequisite: consent of Department.


PMCOL 510 - Advanced Topics View Available Classes

★ 3 (fi 6)(FIRST, 3-0-0)
There is no available course description.

PMCOL 511 - Advanced Topics View Available Classes

★ 3 (fi 6)(SECOND, 3-0-0)
There is no available course description.

PMCOL 512 - Pharmacology of the Synapse View Available Classes

★ 3 (fi 6)(EITHER, 3-0-0)

Current concepts of neurotransmitters, neuromodulators and trophic factors are discussed in the context of the normal, diseased and developing nervous systems. Students should have some biological background either in physiology, pharmacology, zoology, or the neurosciences. Prerequisite: consent of Department.


PMCOL 515 - Advanced Topics in Cardiovascular Pharmacology View Available Classes

★ 3 (fi 6)(EITHER, 3-0-0)

Critical discussion and analysis of current research papers in cardiovascular pharmacology, grouped into themes. Recent developments and use of the literature will be emphasized. In-class participation during round table discussion to critique assigned papers is essential. Each theme will be accompanied by the student's written analyses of papers assigned but not discussed in class, in the format of a condensation/critique. Prerequisite: consent of the Department.


PMCOL 525 - Problem Solving in Pharmacology and Therapeutics View Available Classes

★ 3 (fi 6)(EITHER, 3-0-0)

Students will be presented with problem cases involving patients with conditions, possibly needing drug therapy. They will identify the issues needing resolution, work collectively to find information to resolve them, and present these and their application to each patient to the group. The group will work to resolve outstanding issues after the presentations. Intended for graduate students. Prerequisites: PMCOL 343 and 344 and consent of Instructor.


PMCOL 550 - Introduction to the Pharmacology of Diabetes View Available Classes

★ 3 (fi 6)(EITHER, 3-0-0)

This course is intended for graduate students and will provide an overview of the current understanding of blood glucose homeostasis, insulin secretion and action, the actions of other important blood sugar-regulating hormones and the pathology of diabetes. Current pharmacological approaches for lowering blood glucose will be discussed, as will the latest experimental approaches in identifying potential drug targets and new treatments for diabetes. At the end of the course, students should have an appreciation for the mechanisms that control glucose homeostasis in health and diabetes, the diversity of drug targets and mechanisms by which diabetes drugs promote glucose control, and current rationale and lines of research leading to potential new treatments. Prerequisites: PMCOL 343 and 344 or consent of Department.


PMCOL 575 - Signal Transduction Systems as Pharmacological Targets View Available Classes

★ 3 (fi 6)(EITHER, 3-0-0)

Regulation of various aspects of cell regulation, including proliferation, differentiation, metabolism, survival, motility, and gene transcription, occur mainly via protein phosphorylation in a complex array of well-organized signal transduction pathways. This course will cover topics related to the pharmacological investigation of cellular transduction systems, the discovery of small molecules that alter cell signaling, and how pharmacological manipulation of these signaling pathways may be useful in the drug treatment of a diverse range of diseases, including metastatic, cardiovascular, inflammatory, immune, metabolic and neurodegenerative diseases. Prerequisites: Consent of Department.


PMCOL 612 - Drugs and the Nervous System View Available Classes

★ 3 (fi 6)(EITHER, 3-0-0)

Pharmacological management of disease in the central nervous system is presented in the context of current knowledge of neuroscience and neurochemistry. Prerequisites: consent of the Department.