LABMP 580 - Molecular Diagnostics: Qualitative and Quantitative Techniques

3 units (fi 6)(FIRST, 3-0-1)

This course covers topics including nucleic acid isolation, manipulation of RNA/DNA, separation and detection, nucleic acid amplification, assay design and troubleshooting. This is a bichronous course, content will be delivered through asynchronous lectures, and synchronous seminars. This course is designed primarily for students enrolled in the Specialization in Molecular Diagnostics program, or by permission from the Department.

LABMP 581 - Techniques in Molecular Biology

3 units (fi 6)(EITHER, 1-0-5)

A laboratory course emphasizing introductory and advanced techniques in molecular biology (MLSCI 481). Isolation of RNA, construction of cDNA, amplification of DNA by the real time polymerase chain reaction, analysis of DNA by restriction digestion, transfection of eukaryotic cells for protein expression and Western blotting analysis. Prerequisites: GENET and BIOCH 200 and BIOCH 330 and consent of the Department. An oral presentation on a topic in molecular biology will be required. This course is designed for graduate students. Credit may only be obtained in one of MLSCI 481 or LABMP 581.

LABMP 584 - Molecular Diagnostics: Constitutive Cytogenetics

3 units (fi 6)(FIRST, 3-0-1)

This course covers topics including the identification of normal and abnormal human chromosomes and associated laboratory techniques. This course will focus on constitutive abnormalities and utilize ISCN nomenclature. This is a bichronous course, content will be delivered through asynchronous lectures, and synchronous seminars. This course will utilize an external online platform for karyotyping. This course is designed primarily for students enrolled in the Specialization in Molecular Diagnostics program, or by permission from the Department.

LABMP 595 - Laboratory Management

3 units (fi 6)(EITHER, 0-3S-0)

This seminar course offers topics for consideration in the administration of the clinical laboratory. Topics include clinical laboratory management, finance, organizational behavior, change management, human resources and quality systems. This course is designed primarily for students in the Department of Laboratory Medicine and Pathology, by permission from the Department.

LABMP 602 - Molecular Diagnostics: Clinical Practicum I

3 units (fi 6)(VAR, VARIABLE)

As a part of practicum education for the Molecular Diagnostics specialization, this course will provide a rotation in medical genetics laboratory, (and additional molecular laboratory experiences, as available). The student will be expected to cover specific competencies and objectives and keep a record of cases encountered. Designated preceptors will guide student learning and continuously assess student progress. Prerequisites: LABMP 580, 582, 583 and permission of the department. (Restricted to MSc Molecular Diagnostics specialization.)

MLSCI 481 - Techniques in Molecular Biology

3 units (fi 6)(EITHER, 1-0-5)

A laboratory course emphasizing introductory and advanced techniques in molecular biology. Isolation of RNA, construction of cDNA, amplification of DNA by the real time polymerase chain reaction, analysis of DNA by restriction digestion, transfection of eukaryotic cells for protein expression and Western blot analysis. Prerequisites: BIOL 207 and BIOCH 200 or equivalent and consent of the Division. This course is designed for senior undergraduate students. Credit may only be obtained in one of MLSCI 481 or LABMP 581.

LABMP 582 - Molecular Diagnostics: Variant Analysis

3 units (fi 6)(SECOND, 3-0-1)

This course covers topics including nucleic acid sequencing, microarray, optical genome mapping technologies and data analysis. This course will include HGVS nomenclature and the clinical interpretation of variants. This is a bichronous course, content will be delivered through asynchronous lectures, and synchronous seminars. This course is designed primarily for students enrolled in the Specialization in Molecular Diagnostics program, or by permission from the Department. Prerequisite LABMP 580.

LABMP 585 - Molecular Diagnostics: Somatic Cytogenetics

3 units (fi 6)(SECOND, 3-0-1)

This course covers topics including the identification of abnormal human chromosomes and associated laboratory techniques. This course will focus on somatic abnormalities and utilize ISCN nomenclature. This is a bichronous Course, content will be delivered through asynchronous lectures, and synchronous seminars. This course will utilize an external online platform for karyotyping. This course is designed primarily for students enrolled in the Specialization in Molecular Diagnostics program, or by permission from the Department. Prerequisite LABMP 584.

LABMP 587 - Molecular Diagnostics: Cancer

3 units (fi 6)(SECOND, 3-0-0)

This course introduces the learner to the underlying genetic mechanisms of cancer. The course will focus diagnostic, prognostic and predictive testing for lymphoproliferative disorders such as CLL and ALL, as well as cancer genetic susceptibility syndromes such as Lynch syndrome and breast cancer syndromes. This is an asynchronous course all course content and assessments will be delivered online. This course is designed for students enrolled in FoMD graduate studies, or by permission from the Department.

LABMP 603 - Molecular Diagnostics: Clinical Practicum II

3 units (fi 6)(VAR, VARIABLE)

As a part of practicum education for the Molecular Diagnostics specialization, this course will provide a rotation in human cytogenetic laboratory, (and additional molecular laboratory experiences, as available). The student will be expected to cover specific competencies and objectives and keep a record of cases encountered. Designated preceptors will guide student learning and continuously assess student progress. Prerequisites: LABMP 584, 585, 586 and permission of the department. (Restricted to MSc Molecular Diagnostics specialization.)