BIOL 201 - Eukaryotic Cellular Biology

3 units (fi 6)(EITHER, 3-0-0)

A structural and functional dissection of a eukaryotic cell. Detection of specific molecules at the ultrastructural level; plasma membrane structure and function; cytoskeleton involvement in intracellular transport, mitosis, and cytokinesis; the endomembrane system, protein targeting, exocytosis and endocytosis; nuclear structure and function; cell cycle control and cancer. Prerequisite: BIOL 107 and a 100-level Chemistry course. Note: Not to be taken by students with credit in CELL 201, in addition, not available to students currently enrolled in CELL 201.

GENET 390 - Gene Manipulation

3 units (fi 6)(FIRST, 3-0-0)

Examination of fundamental techniques employed in molecular biological research relevant to both prokaryotic and eukaryotic systems. Topics will provide the theoretical basis appropriate for molecular research in a diverse range of fields including genetics, microbiology, cell biology, biotechnology, evolution and population biology. Prerequisite: BIOL 207; BIOCH 200 or 205 or BIOCH 220; GENET 270 recommended.

GENET 415 - Current Topics in Bacterial Genetics

3 units (fi 6)(FIRST, 3-0-0)

The goal of the course is to build knowledge about conserved, fundamental cellular processes uncovered using genetic approaches to study bacteria and to develop an appreciation for the application of this information to the development of technology and the understanding of human diseases. Prerequisites: Two GENET 300 level courses or MICRB 316 and one GENET 300 level course; this course is normally recommended for fourth-year students. Credit cannot be obtained for both GENET 415 and 515.

GENET 515 - Advanced Current Topics in Bacterial Genetics

3 units (fi 6)(FIRST, 3-0-0)

The goal of the course is to build knowledge about conserved, fundamental cellular processes uncovered using genetic approaches to study bacteria and to develop an appreciation for the application of this information to the development of technology and the understanding of human diseases. Scheduled classes are the same as GENET 415, but with additional assignments and evaluation appropriate to graduate studies. Prerequisite: consent of instructor. Credit cannot be obtained for both GENET 415 and 515.

GENET 418 - Human Genetics

3 units (fi 6)(SECOND, 3-1S-0)

A survey of human genetic variation and mutation in a molecular genetics context. Molecular basis of diseases and applications to genetic counseling and screening, chromosomal abnormalities, genomic imprinting, cancer genetics, gene mapping, population genetics, multifactorial inheritance, gene therapy, and ethical issues. Prerequisites: any two GENET 300-level lecture courses, GENET 302 is recommended. Credit cannot be obtained for both GENET 418 and 518.

GENET 422 - Current Topics in Developmental Genetics

3 units (fi 6)(EITHER, 0-3S-0)

Discussion of selected topics in developmental biology with an emphasis on the cellular and genetic mechanisms used to uncover regulatory pathways. Selection of topics will depend, in part, on the interests of the students enrolled. Peer evaluation will be an integral part of the course and an introduction to the review process in science will be included. Critical reading and analysis of the primary literature, research proposal-based reading and writing, and classroom presentation skills may all be used as means of evaluation. Prerequisites: consent of instructor and GENET 412 or ZOOL 303 or equivalent course in developmental biology.

GENET 518 - Advanced Human Genetics

3 units (fi 6)(SECOND, 3-1S-0)

A survey of human genetic variation and mutation in a molecular genetics context. Molecular basis of diseases and applications to genetic counseling and screening, chromosomal abnormalities, genomic imprinting, cancer genetics, gene mapping, population genetics, multifactorial inheritance, gene therapy, and ethical issues. Scheduled classes are the same as GENET 418, but with additional assignments and evaluation appropriate to graduate studies. Prerequisite: consent of instructor. Credit cannot be obtained for both GENET 418 and 518.