Christopher Cairo, PhD

Professor, Faculty of Science - Chemistry

Winter Term 2021 (1740)

CHEM 454 - Bioconjugate Chemistry

★ 3 (fi 6)(EITHER, 3-0-0)

Discussion of organic reactions to modify or label biopolymers including proteins, carbohydrates, and nucleic acids. Topics will include mechanistic and methodological details of commonly employed reactions used for chemoselective labeling or modification of biomolecules to produce synthetic vaccines, antibody-drug conjugates, and native chemical ligation will be discussed. Prerequisites: CHEM 361 and BIOCH 200, or consent of instructor. Note: This course may not be taken for credit if credit has already been received in CHEM 464.

LECTURE B1 (42856)
2021-01-11 - 2021-04-16
TH 12:30 - 13:50 (TBD)


CHEM 554 - Bioconjugate Chemistry

★ 3 (fi 6)(EITHER, 3-0-0)

Graduate-level discussion of organic reactions to modify or label biopolymers including proteins, carbohydrates, and nucleic acids. Topics will include mechanistic and methodological details of commonly employed reactions used for chemoselective labeling or modification of biomolecules to produce synthetic bioconjugates. Applications including synthetic vaccines, antibody-drug conjugates, and native chemical ligation will be discussed. Prerequisite: 1 year of introductory organic chemistry and 1 term of biochemistry, or consent of instructor. Not open to students with credit in CHEM 464 or 564.

LECTURE B1 (42858)
2021-01-11 - 2021-04-16
TH 12:30 - 13:50 (TBD)