LABMP - Laboratory Medicine and Pathology

Lecture sessions on the study of human disease are presented. The causes and general mechanisms of disease with selected specific examples from various organ systems are discussed. Disease related structural and functional changes at the molecular, cellular and tissue level are presented, and how these changes can be appreciated by various laboratory methods. The discipline bridges basic science and clinical medicine. Prerequisites: PHYSL *6, BIOCH *3. Credit can be obtained in only 1 of LABMP 400 or LABMP 500

Lecture sessions on the study of human disease are presented (LABMP 400). The causes and general mechanisms of disease with selected specific examples from various organ systems are discussed. Disease related structural and functional changes at the molecular, cellular and tissue level are presented, and how these changes can be appreciated by various laboratory methods. A written review of scientific literature on a specific topic in Pathology will be required. Prerequisites: Credit may only be obtained in one of LABMP 400 or LABMP 500.

This course presents advanced level theory and practice in immunohematology as it relates to transfusion medicine. Topics covered include blood group genetics, and classification, immune hemolysis, factors influencing clinical significance of blood antigen-antibody interactions, as well as investigations and management of perinatal and alloantibodies. Course content will be delivered through lectures, seminars and workshops as well as directed reading, and will include a clinical practicum at an approved clinical transfusion service laboratory and/or a portfolio of work experiences. This course is designed primarily for students enrolled in the Specialization in Transfusion Science program, or by permission from the Department.

This course presents advanced level immunohematology methods as they relate to transfusion medicine. Topics covered include blood cell genotyping methods, the development of monoclonal reagents and solid-phase and microcolumn platforms for performing the pre-transfusion tests, cellular, serology and microarray and other techniques for in vitro measurements of the antigen-antibody reactions. Course content will be delivered through lectures, seminars and workshops as well as directed reading, and will include a clinical practicum at an approved clinical transfusion service laboratory and/or a portfolio of work experiences. This course is designed primarily for students enrolled in the Specialization in Transfusion Science program, or by permission from the Department.

This course covers topics from blood donation to transfusion, including the management of collection, production, testing, storage, and distribution of components and products for routine transfusion. Course content will be delivered through lectures, seminars and workshops as well as directed reading, and will include a clinical practicum at an approved clinical transfusion service laboratory and/or a portfolio of work experiences. This course is designed primarily for students enrolled in the Specialization in Transfusion Science program, or by permission from the Department.

This course covers topics from blood donation to transfusion, including the management of collection, production, testing, storage, and distribution of blood components and products for transfusion in special clinical indications, including stem cell and solid organ transplant. Course content will be delivered through lectures, seminars and workshops as well as directed reading, and will include a clinical practicum at an approved clinical transfusion service laboratory and/or a portfolio of work experiences. This course is designed primarily for students enrolled in the Specialization in Transfusion Science program, or by permission from the Department. Prerequisites: LABMP 503.

This course covers theory of specific clinical disorders requiring advanced transfusion knowledge. Topics include the management of hematological disorders, transplantation, perinatal and massive transfusion support. Course content will be delivered through lectures, seminars and workshops as well as directed reading, and will include a clinical practicum at an approved clinical transfusion service laboratory and/or a portfolio of work experiences. This course is designed primarily for students enrolled in the Specialization in Transfusion Science program, or by permission from the Department. Prerequisites: LABMP 501 and LABMP 502.

This course covers topics related to the Quality Systems Essentials as they apply to the management of a transfusion service and blood supplier. In addition, topics in laboratory management including personnel, laboratory information systems and equipment as well as method validation and proficiency testing will be reviewed. Course content will be delivered through lectures, seminars and workshops as well as directed reading, and will include a clinical practicum at an approved clinical transfusion service laboratory and/or a portfolio of work experiences. This course is designed primarily for students enrolled in the Specialization in Transfusion Science program, or by permission from the Department.

Physiochemical changes in aqueous solutions at low temperatures and responses of living cells and tissues to those changes. Current theories of damage and protection during freezing and thawing. Prerequisite: consent of Department. This course may not be taken for credit if credit has already been received in PATH 510.

This course is designed to develop the skills of graduate students in the areas of critical review of clinical and basic science literature, experimental study design, research ethics, concepts in oral and poster presentations of scientific research, abstract writing for clinical and basic science conferences, as well as how to maximize the scientific conference experience. Active class discussion is a component of each lecture, with group and individual assignments to give practical experiences to each student immediately applicable to their graduate research program. Open to graduate students and clinical residents in the Faculty of Medicine and Dentistry. Students from other faculties may register with consent of the instructors.

Topics covered will include advanced flow cytometer principles, staining principles, instrument maintenance, quality control, and data analysis. Emphasis on the use/applications of flow cytometry in clinical environments. This course is designed for graduate students. Credit may only be obtained in one of MLSCI 435 or LABMP 536.

Reading and study of basic laboratory medicine and pathology topics relevant to the student's chosen field of study under the direction of one or more faculty members. Prerequisite: Consent of Graduate Co-ordinator, Laboratory Medicine and Pathology.

Students will integrate knowledge and practical skills in the areas of environmental chemistry and toxicology. The student will learn to predict how chemicals can move and transform in the environment based on physical and chemical properties, how this affects human and environmental exposure, and consequences thereof for health. The basic principles of toxicology will be taught and students will gain appreciation for the diversity of physiological and/or biochemical mechanisms by which toxicants cause their adverse effects, and the various defenses our bodies have evolved to employ. Open to graduate students in Laboratory Medicine and Pathology. Students from other departments may register with consent of the instructor.

Theory and practice of laboratory research techniques and methods. Fundamentals and applications of quantitative analysis, separation, atomic spectrometry, mass spectrometry, PCR and cloning with laboratory experiments. For students who will perform laboratory research. This course may not be taken for credit if credit has been received in PHS 513. Prerequisite: Consent of the instructor.

This course will help students develop the understanding and skills to apply research results to real world needs for the management of risks posed by environmental contaminants as well as the development of regulation and policy involving such management. Open to graduate students in Laboratory Medicine and Pathology. Students from other departments may register with consent of the instructor.

This course will focus on hazardous toxicant identification and assessment of effects. It will examine exposure and effects of toxicants on a number of different levels including a) molecular effects, b) tissue effects, c) individual and organismal effects, and d) population effects. Case studies will be used to illustrate different applications and the utilization of specific approaches to hazard identification and assessment. The concept of Adverse Outcome Pathways (AOPs) will be introduced and students will be responsible for developing their own AOP for a specific toxicity.

Topics covered will include advanced mass spectrometry principles, sample preparation instrument maintenance, quality control, and data analysis. Qualitative, quantitative and clinical applications of mass spectrometry will be covered. Emphasis on the use/applications mass spectrometry in clinical environments. This course is designed for graduate students. Credit may only be obtained in one of MLSCI 461 or LABMP 561.

The course provides a realistic, practical discussion on the role of diagnostic and public health microbiology laboratories in North America. It is designed to enhance the student's ability to assimilate new and specialized knowledge in an evolving clinical microbiology discipline from a multisectoral OneWorld Health perspective. The course content will revolve around case presentations related to current clinical microbiology topics, including diagnostic bacteriology, virology, mycology, parasitology, molecular diagnostic techniques, infection control and prevention strategies as well as new microbiology diagnostic technologies and emerging pathogens. Open to graduate students in Laboratory Medicine and Pathology. Other students and clinical residents may register with the consent of the department. Prerequisites: Credit can be obtained in only one of MLSCI 470 or LABMP 570.

A laboratory course emphasizing introductory and advanced techniques in molecular biology (MLSCI 481). Isolation of RNA, construction of cDNA, amplification of DNA by the real time polymerase chain reaction, analysis of DNA by restriction digestion, transfection of eukaryotic cells for protein expression and Western blotting analysis. Prerequisites: GENET and BIOCH 200 and BIOCH 330 and consent of the Department. An oral presentation on a topic in molecular biology will be required. This course is designed for graduate students. Credit may only be obtained in one of MLSCI 481 or LABMP 581.

A lecture and seminar course describing the future effects of technology on medicine in both the developed and developing world, the promise and perils of biotech, nanotech, and artificial intelligence, and changing character of research and practice of medicine and pathology in the coming decades, and the technological singularity. Each student will carry out a project supervised by a faculty member and give a presentation. This course is designed for graduate students in the Faculties of Medicine, Science, or Arts, and is open to undergraduates in those Faculties with consent of Department.

This course will provide an in-depth review of body organ systems and disease through lectures and seminars. This course is designed primarily for students enrolled in the Pathologists' Assistant specialization.

This course will provide an in-depth review of body organ systems and disease through lectures and seminars. This course is designed primarily for students enrolled in the Pathologists' Assistant specialization.

This course will provide an introduction to the role of the Pathologists' Assistant in the clinical laboratory and principles of techniques used in the anatomic pathology laboratory, along with interactive demonstrations. Topics will include laboratory safety, review of specimen types encountered in the laboratory, specimen handling, submission of tissue and material for ancillary studies, gross description and dissection techniques, autopsy techniques, and photography. This course is designed primarily for students enrolled in the Pathologists' Assistant specialization.

This seminar course offers topics for consideration in the administration of the clinical laboratory. Topics include finance, organizational behavior, change management, human resource management, collective agreements, safety, risk management, ethics, the Health Professions Act, equipment acquisition, contracts, accreditation, and materials management. This course is designed primarily for students enrolled in the Pathologists' Assistant specialization.

This seminar course offers topics for consideration in the administration of the clinical laboratory. Topics include finance, organizational behavior, change management, human resource management, collective agreements, safety, risk management, ethics, the Health Professions Act, equipment acquisition, contracts, accreditation, and materials management. This course is designed primarily for students enrolled in the Pathologists' Assistant specialization.

As a part of practicum education for the Pathologists' Assistant specialization, this course will provide rotations in laboratory medicine that include clinical biochemistry, clinical hematology and transfusion medicine, clinical microbiology, and clinical histology, as well as rotations in the pathology laboratories that include autopsy, surgical pathology, pediatric pathology and forensic pathology. The student will be expected to cover specific competencies and objectives and keep a record of cases encountered. A designated preceptor in each rotation will guide student learning and continuously assess student progress.

As a part of practicum education for the Pathologists' Assistant specialization, this course will provide rotations in laboratory medicine that include clinical biochemistry, clinical hematology and transfusion medicine, clinical microbiology, and clinical histology, as well as rotations in the pathology laboratories that include autopsy, surgical pathology, pediatric pathology and forensic pathology. The student will be expected to cover specific competencies and objectives and keep a record of cases encountered. A designated preceptor in each rotation will guide student learning and continuously assess student progress.

As a part of practicum education for the Pathologists' Assistant specialization, this course will provide rotations in laboratory medicine that include clinical biochemistry, clinical hematology and transfusion medicine, clinical microbiology, and clinical histology, as well as rotations in the pathology laboratories that include autopsy, surgical pathology, pediatric pathology and forensic pathology. The student will be expected to cover specific competencies and objectives and keep a record of cases encountered. A designated preceptor in each rotation will guide student learning and continuously assess student progress.

As a part of practicum education for the Pathologists' Assistant specialization, this course will provide rotations in autopsy, surgical pathology, pediatric pathology and forensic pathology. The student will be expected to cover specific competencies and objectives and keep a record of cases encountered. A designated preceptor in each rotation will guide student learning and continuously assess student progress.

As a part of practicum education for the Pathologists' Assistant specialization, this course will provide rotations in autopsy, surgical pathology, pediatric pathology and forensic pathology. The student will be expected to cover specific competencies and objectives and keep a record of cases encountered. A designated preceptor in each rotation will guide student learning and continuously assess student progress.

As a part of practicum education for the Pathologists' Assistant specialization, this course will provide rotations in autopsy, surgical pathology, pediatric pathology and forensic pathology (and additional community-based experiences, as available). The student will be expected to cover specific competencies and objectives, and keep a record of cases encountered. A designated preceptor in each rotation will guide student learning and continuously assess student progress.

As a part of practicum education for the Pathologists' Assistant specialization, this course will provide rotations in autopsy, surgical pathology, pediatric pathology and forensic pathology (and additional community-based experiences, as available). The student will be expected to cover specific competencies and objectives, and keep a record of cases encountered. A designated preceptor in each rotation will guide student learning and continuously assess student progress.

As a part of practicum education for the Pathologists' Assistant specialization, this course will provide rotations in autopsy, surgical pathology, pediatric pathology and forensic pathology (and additional community-based experiences, as available). The student will be expected to cover specific competencies and objectives, and keep a record of cases encountered. A designated preceptor in each rotation will guide student learning and continuously assess student progress.

As a part of clinical laboratory practicum education for the Transfusion Science specialization, this course will provide rotations in blood banks, hospitals and cell therapy laboratories. The student will be expected to cover specific competencies and objectives and keep a record of cases encountered. A designated preceptor in each rotation will guide student learning and continuously assess student progress. Prerequisites: LABMP 501 and 502 and permission of the department. (Restricted to MSc Transfusion Science specialization.)

As a part of clinical laboratory practicum education for the Transfusion Science specialization, this course will provide rotations in blood banks, hospitals and cell therapy laboratories. The student will be expected to cover specific competencies and objectives and keep a record of cases encountered. A designated preceptor in each rotation will guide student learning and continuously assess student progress. Prerequisites: LABMP 501 and 502 and permission of the department. (Restricted to MSc Transfusion Science specialization.)

The course is an independent research project. Seminar sessions cover topics relevant to conducting independent research studies. The student will be expected to write a research proposal, keep an accurate notebook, and conduct adequate investigative research. The project will be written as a research paper and presented at departmental rounds. This course is designed primarily for students enrolled in the Pathologists' Assistant specialization.

The course is an independent research project. Seminar sessions cover topics relevant to conducting independent research studies. The student will be expected to write a research proposal, keep an accurate notebook, and conduct adequate investigative research. The project will be written as a research paper and presented at departmental rounds. This course is designed primarily for students enrolled in the Pathologists' Assistant specialization.