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3 units (fi 6)(FIRST, 3-0-0) Open Study: Open

The diversity of microscopic life forms, both prokaryotic (bacteria and archaea) and eukaryotic (protists, fungi, phytoplankton), will be explored. The evolutionary forces responsible for this diversity will be described in detail and contrasted to those at work in macroscopic eukaryotes. Students will learn about the molecular methods used to identify and classify both culturable and non-culturable microbes, and genetically characterize entire populations. Prerequisites: BIOL 107 and 108 or SCI 100, and a 200-level Biological Sciences course. MICRB 265 recommended.

3 units (fi 6)(SECOND, 3-0-3) Open Study: Open

Expands on prior introductions to the scientific method and examines the steps involved in the planning, collection, organization, analysis and presentation of biological data. Classes will explore the types of data used to answer a variety of biological questions and will review several different sampling designs, assess the benefits and limitations of various data types for scientific inference, and integrate the statistical methods that are common to other introductory courses. Labs will teach students how spreadsheets and relational databases can be used to manipulate, analyze, and present the results of scientific research. Prerequisites: BIOL 208 and STAT 151 or SCI 151.

3 units (fi 6)(EITHER, 3-3S-0) Open Study: Open

Principles of community ecology, applied to plants and animals. The nature of communities, functional groups and rarity; niche theory and competition; disturbance and other alternatives to competition; food webs (predation, herbivory and disease); diversity (determinants, functional consequences and gradients); island communities. Prerequisites: BIOL 208; STAT 151 or SCI 151; and any one of MATH 113, 114, 115, 120, 125 or SCI 100. May not be taken for credit if credit already obtained in ZOOL 332.

3 units (fi 6)(FIRST, 3-0-3) Open Study: Open

The course includes an introduction to the hydrology, biogeochemistry and ecology of wetland ecosystems. Topics covered include classification, geomorphic setting, distribution, functions and ecosystem services of wetlands. Human use, alteration and management of wetlands are examined. An emphasis is placed on wetlands and wetland management in Western Canada, including boreal peatlands and prairie marshes. A full day field trip on a Saturday is required. Prerequisite: one of BIOL 208, REN R 250, or EAS 201. Credit may be obtained in only one of BIOL 333 and REN R 333. This course requires payment of additional student instructional support fees. Refer to the Tuition and Fees page in the University Regulations section of the Calendar.

3 units (fi 6)(SECOND, 3-1S-0) Open Study: Open

An introduction to the principles, methods, and applications of biological systematics, including reconstruction of phylogenies, creation of classifications, historical biogeography, and applications in evolutionary biology. Each student will analyze phylogenetic data and write a description of a species and its relationships. Prerequisite: BIOL 108 or SCI 100 and a 200-level Biological Sciences course; BIOL 221 strongly recommended.

3 units (fi 6)(EITHER, 3-0-0) Open Study: Open

An overview of the adverse effects of chemicals or physical agents on biological systems in an ecological context. This course takes a multidisciplinary approach to understanding biological effects and their assessment. Prerequisites: BIOL 208; ZOOL 241 or PHYSL 210 or 212 or 214; and CHEM 261.

3 units (fi 6)(SECOND, 0-0-6) Open Study: Open

Critical discussion and use of techniques for characterizing macromolecules from prokaryotic and eukaryotic systems. This course provides the theoretical and hands-on experience required to use classic and cutting-edge technologies to characterize the properties of these macromolecules. Prerequisite: BIOL 207, BIOL 391, and BIOCH 200, or consent of Department. Credit can only be obtained for one of BIOL 343 or 543 or MICRB 343 or 345.

3 units (fi 6)(SECOND, 3-0-0) Open Study: Open

An introduction to marine science and marine biology including history of marine exploration, essential features of the physical marine environment, a survey of major marine communities and adaptations of the organisms that live in each, overviews of selected groups of marine organisms (e.g., marine mammals), and human impact on the oceans. Recommended as preparation for courses offered through the Bamfield Marine Station (see courses listed under MA SC). Prerequisite: ZOOL 250 or BIOL 208.

3 units (fi 6)(FIRST, 3-1S-0) Open Study: Open

An introduction to the ecology of freshwater ecosystems. Lectures will examine the roles of biota in ecological patterns and processes in lakes, ponds, rivers, and streams, emphasizing north-temperate and boreal regions. Seminars will focus on recent papers from the primary literature. Designed to stand-alone or to provide a biological complement to BIOL 464. Prerequisite: BIOL 208.

3 units (fi 6)(FIRST, 1-0-3) Open Study: Open

A practical course introducing students to techniques used in the field and lab to biomonitor lakes and streams. Topics covered will include plankton production and composition, fish and benthos community structure, herbivory and predation, and paleolimnology. The laboratory component includes field trips and independent research projects. Pre or corequisite: BIOL 364 or permission of instructor.

3 units (fi 6)(SECOND, 3-0-0) Open Study: Open

Examines the ecology of boreal and arctic ecosystems, including postglacial history, climate, geology, nutrient cycling and energy flow in forests, wetlands, lakes and marine systems, animal and plant adaptations to cold and current human impacts. Prerequisite: BIOL 208. Credit cannot be obtained for BIOL 366 and any of the following courses: REN R 365, 463, 466.

3 units (fi 6)(FIRST, 3-0-0) Open Study: Open

This course introduces the principles of conservation biology with an emphasis on ecological processes operating at population, community and ecosystem levels of organization. Threats to biological diversity, ranging from species introductions to habitat destruction will be discussed along with conservation solutions ranging from the design of protected areas through conservation legislation. Prerequisite: BIOL 208. Credit cannot be obtained in both BIOL 367 and REN R 364.

3 units (fi 6)(SECOND, 3-1S-0) Open Study: Open

Application of molecular biology to the study of systematics, structure of natural populations, mating systems, and forensics. Among the topics discussed are molecular techniques used to detect genetic variation in natural populations, methods to construct phylogenies using molecular data, mathematical models of population structure, paternity analysis, and DNA fingerprinting. Prerequisite: BIOL 207. BIOL 221 recommended.

3 units (fi 6)(FIRST, 3-0-0) Open Study: Open

This course examines how humankind's collective activities, including altering the climate, have significantly affected the natural planetary balance. We will discuss human population growth and unsustainable resource use; the movement of pollutants through the atmosphere, hydrosphere and biosphere; the impacts these stressors have on ecosystem services and human health; and how certain impacts have been and can be mitigated by environmental policies and laws. Prerequisite: BIOL 208.

3 units (fi 6)(SECOND, 3-0-0) Open Study: Open

Ecological impacts of climate change and large-scale human activities on terrestrial and aquatic ecosystems. The focus of this course is to learn to write brief technical summaries of current environment issues, in a fashion that can be understood by an educated citizen. Topics such as climate change, water management projects, invasion of exotic species and national parks management are presented as the forum to evaluate options, trade-offs and solutions to environmental social issues. Prerequisites: BIOL 208; BOT 205 recommended.

3 units (fi 6)(EITHER, 0-0-6)

A review of the scientific literature on a biological topic, done under the supervision of an academic member of the Department of Biological Sciences. A co-supervisor, who may be outside the Department, may be involved at the supervisor's discretion. Completion of this course requires a written report on the information gleaned from the literature. Prerequisites: A 200-level Biological Sciences course, and consent of Department.

3 units (fi 6)(EITHER, 0-1S-6) Open Study: Open

A laboratory course introducing students to techniques in gene manipulation, protein expression and bioinformatics by following a gene through a thematic series of molecular manipulations. Prerequisites: BIOL 207 and BIOCH 200 or consent of Department. Not to be taken by students currently enrolled in GENET 420 or with credit in GENET 420. Credit can be obtained for only one of BIOL 391, IMIN 391 or MMI 391.

3 units (fi 6)(SECOND, 0-1S-6) Open Study: Open

A laboratory course introducing students to current molecular biology techniques and associated analyses used to study population genetics, systematics, and evolutionary biology in natural populations. Students will develop microsatellite marker systems and use them to examine the genetic structure of a natural population. A comparative bioinformatic approach will be used to generate sequence data to investigate the use of single nucleotide polymorphisms in candidate gene analysis and in phylogenetic inference. Prerequisite: BIOL 207 and BIOL 208. Co- or Pre-requisite: BIOL 380. Note: BIOL 392 and 592 cannot both be taken for credit.

3 units (fi 6)(EITHER, VARIABLE) Open Study: Open, Spring / Summer

Covers special topics of current interest in biology pertaining specifically to field opportunities. This course may be held outside of Edmonton at one or more off-campus locations either domestically or internationally, and may require additional on-campus coursework. This course requires payment of additional miscellaneous fees. Refer to the Tuition and Fees page in the University Regulations section of the Calendar. See departmental website for BIOL 395 offered sections. Prerequisite: second year Biological Sciences course and permission of instructor. Credit for this course may be obtained more than once.

3 units (fi 6)(EITHER, 0-0-6) Open Study: Open

Directed research done under the supervision of an academic member of the Department of Biological Sciences. Normally for students in their third year of study. Successful completion of this course requires a written report on the research project. Prerequisites: A 200-level Biological Sciences course and consent of the Associate Chair, Undergraduate Studies. Credit for this course may be obtained only once.

3 units (fi 12)(TWO TERM, 0-0-6) Open Study: Open

Directed research done under the supervision of an academic member of the Department of Biological Sciences. Normally for students in their third year of study. Successful completion of this course requires a written report on the research project. Prerequisites: A 200-level Biological Sciences course and consent of the Associate Chair, Undergraduate Studies. Credit for this course may be obtained only once.

3 units (fi 12)(TWO TERM, 0-0-6) Open Study: Open

Directed research done under the supervision of an academic member of the Department of Biological Sciences. Normally for students in their third year of study. Successful completion of this course requires a written report on the research project. Prerequisites: A 200-level Biological Sciences course and consent of the Associate Chair, Undergraduate Studies. Credit for this course may be obtained only once.

3 units (fi 6)(FIRST, 0-3S-0)

This course will use a combination of approaches to evaluate the origins and modern usage of foundational ideas and studies in ecology. Topics may include diversity gradients, niche theory, life-histories & strategies, multi-trophic networks and ecological stability. Prerequisites: BIOL 208 and 6 units from Ecology, Evolution and Environmental Biology List C. Credit cannot be obtained for both BIOL 408 and BIOL 508.

3 units (fi 6)(FIRST, 3-0-0) Open Study: Open

This course will examine the biology of zoonotic agents and the implication of host-pathogen interactions to disease susceptibility and resistance. Students will apply these basic concepts towards the understanding of issues governing pathogenesis, pathology, epidemiology, control and surveillance of zoonotic diseases. Focus will be placed on zoonotic agents currently having a significant impact on animal and public health. Lectures will be followed by active discussion of selected readings. Prerequisites: one of IMIN 200, ZOOL 352, ZOOL 354, or ENT 392. Credit cannot be obtained for both BIOL 409 and BIOL 509.

3 units (fi 6)(FIRST, 0-3S-0)

This course surveys the application of genomic approaches to problems of ecology and organismal evolution. It combines explanation of methodological and conceptual approaches with presentation and discussion of case studies. Topics include adaptation, speciation, genome evolution, metagenomics, population genomics, and functional genomics. Prerequisites: BIOL 207, 208, and 221. Credit cannot be obtained for both BIOL 411 and BIOL 511.

3 units (fi 6)(EITHER, 3-0-3) Open Study: Open

Methods for inferring evolutionary trees and their applications to the fields of comparative biology, molecular evolution, and systematics. Topics to be covered include phylogenetic inference, molecular evolution integrated at the organismal and population level, and evolutionary developmental genetics. Labs emphasize practical experience in data analysis. Prerequisite: BIOL 335 or consent of Department. BIOL 380 or 392 recommended. Credit cannot be obtained for both BIOL 421 and BIOL 521. Offered in alternate years.

3 units (fi 6)(EITHER, 3-0-3) Open Study: Open

Familiarizes the student with the practical aspects of statistical design in biology, the analysis of experimental and survey data, and interpretation of statistical results. Lectures emphasize the rationale for choosing statistical tests and an understanding of their mathematical foundation and framework. Labs and assignments provide hands-on training in data analysis with the R programming language and in the interpretation of software outputs, and stress critical thinking and scientific communication. Prerequisites: STAT 141 or 151 or SCI 151, BIOL 330, and a 300-level Biological Sciences course. Credit cannot be obtained for BIOL 430 and BIOL 530 or REN R 480.

3 units (fi 6)(SECOND, 3-0-3)

Principles of population ecology as they apply to plants and animals; population consequences of variation among individuals; habitat structure and population structure; habitat selection and foraging theory; life tables, demography, and the evolution of life history patterns; population dynamics; interactions among organisms (predation, competition, mutualism, parasites/disease); harvesting; and population regulation. Prerequisites: BIOL 208; BIOL 330; one of MATH 114, 125, 134, 144, or 154; STAT 151 or 161. This course may not be taken for credit if credit has already been obtained in BIOL 331.

3 units (fi 6)(FIRST, 0-0-6) Open Study: Open

Design, execution, analysis, and presentation of problems in behavioral, population, and community ecology in a field environment. Field exercises, demonstration of techniques, and data collection for independent projects will take place during the two weeks preceding the Fall term at a field station off the main campus. Final reports are due in the last week of September. Prerequisites: BIOL 331 or 332 or ZOOL 371 or BOT 332; a statistics course such as STAT 151 or SCI 151, BIOL 330 or 430. This course requires payment of additional miscellaneous fees. Refer to the Tuition and Fees page in the University Regulations section of the Calendar.

3 units (fi 6)(EITHER, 3-0-0) Open Study: Open

Plants and animals are engaged in a diversity of ecological interactions, with implications for evolutionary trajectories, species coexistence, and the delivery of ecosystem services. This course requires active engagement, which may include discussion and debate. Lecture content will include a diversity of advanced topics in ecology and evolutionary biology with a focus on species interactions. Prerequisite: BIOL 331 or 332 or BOT 332 or ZOOL 371.

3 units (fi 6)(EITHER, 0-3S-0) Open Study: Open

An introduction to the broad field of Chemical Ecology through survey, discussion and analysis of current and historical literature. Topics include a wide array of chemically-mediated ecological interactions in a variety of taxa. Studies that analyze the importance of the use of chemical signals for habitat selection, resource acquisition, reproduction, defense and social interactions are discussed. Students research topics in Chemical Ecology and present their findings in oral and written formats. Prerequisite: BIOL 208. CHEM 164 or 261 recommended. Credit cannot be obtained for both BIOL 434 and 534. Offered in alternate years.

3 units (fi 6)(SECOND, 0-3S-0) Open Study: Open

The course will introduce students to theory and techniques employed in the analysis of physical, hydrological, chemical, and ecological properties of ecosystems using a watershed (catchment) approach. Focus will be on landscape interactions or linkages between upland, wetland/riparian, and surface-water in the study of the natural ecohydrologic function and response to disturbance of watershed ecosystems. Emphasis will be placed on Boreal Alberta. Topics are covered through reading the literature and group discussions. Prerequisite: one of BIOL 333, BIOL 340, BIOL 364, EAS 223 or REN R 350, or consent of the Department. Credit cannot be obtained for both BIOL 440 and 540.

3 units (fi 6)(SECOND, 0-3S-0) Open Study: Open

This course explores the intersecting biological, chemical, and geological processes and reactions governing the cycling of elements that control our environment. Course discussions will include consideration of the atmosphere, lithosphere, hydrosphere and biosphere, and will be framed by our understanding that elemental cycling on Earth is fundamentally altered by organisms. Coursework will incorporate current topics in anthropogenic alteration of the natural cycles critical for organismal and planetary function. Prerequisites: CHEM 101 and BIOL 208. Credit cannot be obtained for both BIOL 442 and 542.

3 units (fi 6)(FIRST, 0-3S-0) Open Study: Open

Survey, discussion and evaluation of literature dealing with current advances and selected topics in animal and cell physiology. Prerequisite: ZOOL 340 or 342 or 343, or PHYSL 372 and consent of instructor. Credit may be obtained more than once. Offered in alternate years.

3 units (fi 6)(SECOND, 0-3S-0) Open Study: Open

Seminar and reading course addressing current topics in conservation biology. Prerequisites: BIOL 367 or REN R 364 or consent of instructor.

3 units (fi 6)(SECOND, 3-0-3) Open Study: Open

Landscapes are holistic entities whose patterns influence ecological processes. Topics highlighted in this course include landscape components, morphology and dynamics; detecting spatial/temporal change in landscapes; issues of scales; movements of organisms, disturbances, and nutrients across landscape mosaics; and restoration, planning and management in a landscape context. Labs emphasize GIS applications to characterizing landscape patterns and heterogeneity in space and time, distributing and moving organisms across landscapes, and restoring or planning landscapes for conservation objectives. Prerequisites: MATH 115 or SCI 100; STAT 151 or SCI 151; one of BIOL 331, 332 or BOT 332. Previous GIS course is useful. Credit cannot be obtained for both BIOL 471 and 571.

3 units (fi 6)(EITHER, 0-0-6) Open Study: Open

Registration will be contingent on the student's having made prior arrangements with a faculty member willing to supervise the program. Credit may be obtained more than once. Prerequisites: A 300-level Biological Sciences course and consent of the Associate Chair, Undergraduate Studies.

3 units (fi 6)(EITHER, 0-3S-0) Open Study: Open

Covers specialized topics of current interest to advanced undergraduates in Biological Sciences. Consult the Department for details about current offerings. Prerequisite: consent of instructor. Credit for this course may be obtained more than once.

3 units (fi 6)(EITHER, 3-0-3) Open Study: Open

Covers specialized topics of current interest to advanced undergraduates in Biological Sciences. Consult the Department for details about current offerings. Prerequisite: consent of instructor. Credit for this course may be obtained more than once.

3 units (fi 6)(EITHER, 0-1S-6) Open Study: Open

Covers specialized topics of current interest to advanced undergraduates in Biological Sciences. Consult the Department for details about current offerings. Prerequisite: consent of instructor. Credit for this course may be obtained more than once.

3 units (fi 6)(EITHER, 0-0-6) Open Study: Open

Directed research done under the supervision of an academic member of the Department of Biological Sciences. Normally for students in their fourth year of study. Successful completion of this course requires a written report on the research project. Credit may be obtained more than once. Prerequisites: A 300-level Biological Sciences course and consent of the Associate Chair, Undergraduate Studies.

3 units (fi 12)(TWO TERM, 0-0-6) Open Study: Open

Research project done under the supervision of an academic member of the Department of Biological Sciences, and the co-supervision of a second research mentor. Completion of this course requires an oral presentation and a written report on the research project. Prerequisites: A 300-level Biological Sciences course and consent of Department.

3 units (fi 12)(TWO TERM, 0-0-6) Open Study: Open

Research project done under the supervision of an academic member of the Department of Biological Sciences, and the co-supervision of a second research mentor. Completion of this course requires an oral presentation and a written report on the research project. Prerequisites: A 300-level Biological Sciences course and consent of Department.

3 units (fi 6)(FIRST, 3-1S-0)

Discussion of computational tools and databases used in the analysis of data from high-throughput molecular biology studies. Students will use existing tools, learn the underlying algorithms and their limitations, and will be required to complete an individual research project. Prerequisite: consent of instructor. Credit cannot be obtained for both BIOIN 301 and BIOL 501.

2 units (fi 4)(EITHER, 1-1S-0)

Lectures and discussions on a variety of subjects in systematics and evolutionary biology by graduate students, staff, and visiting speakers. Credit may be obtained more than once. Prerequisite: consent of instructors for students not registered in the systematics and evolution graduate program.

3 units (fi 6)(FIRST, 0-3S-0)

This course will use a combination of approaches to evaluate the origins and modern usage of foundational ideas and studies in ecology. Topics may include diversity gradients, niche theory, life-histories & strategies, multi-trophic networks and ecological stability. Seminars are the same as for BIOL 408 but with additional assignments and evaluations appropriate for graduate studies. Prerequisite: Consent of Department. Credit cannot be obtained for both BIOL 408 and BIOL 508.

3 units (fi 6)(FIRST, 3-0-0)

This course will examine the biology of zoonotic agents and the implication of host-pathogen interactions to disease susceptibility and resistance. Students will apply these basic concepts towards the understanding of issues governing pathogenesis, pathology, epidemiology, control and surveillance of zoonotic diseases. Focus will be placed on zoonotic agents currently having a significant impact on animal and public health. Lectures will be followed by active discussion of selected readings. Scheduled classes are the same as for BIOL 409, but with additional assignments and evaluation appropriate to graduate studies. Prerequisite: consent of instructor. Credit cannot be obtained for both BIOL 409 and BIOL 509.

3 units (fi 6)(FIRST, 3-0-0)

Biological aging is a complex process that involves the progressive deterioration of an organism over time. This course covers the aging process at the molecular, tissue and organismal levels. Topics for discussion include assessment of animal models of aging, mechanisms of aging, healthy aging, age-associated disease and interventions. Lectures are the same as BIOL 310, but with additional assignments and evaluation appropriate to graduate studies. Prerequisite: Consent of instructor. Credit cannot be obtained for both BIOL 310 and BIOL 510.

3 units (fi 6)(FIRST, 0-3S-0)

This course surveys the application of genomic approaches to problems of ecology and organismal evolution. It combines the explanation of methodological and conceptual approaches with presentation and discussion of case studies. Topics include adaptation, speciation, genome evolution, metagenomics, population genomics, and functional genomics. Seminars are the same as for BIOL 411 but with additional assignments and evaluations appropriate for graduate studies. Prerequisites: Consent of Department. Credit cannot be obtained for both BIOL 411 and BIOL 511.

3 units (fi 6)(SECOND, 3-0-0)

Students will use their own thesis research area of molecular and cellular biology for writing for different readers, and for visualizing data in various ways to emphasize critical concepts or facts. They will perform peer review of selected assignments. Students will present a final summary of their assignments to the class. Credit may not be obtained for both BIOL 514 and BIOL 603.

3 units (fi 6)(EITHER, 3-0-3)

Methods for inferring evolutionary trees and their applications to the fields of comparative biology, molecular evolution, and systematics. Topics to be covered include phylogenetic inference, molecular evolution integrated at the organismal and population level, and evolutionary developmental genetics. Labs emphasize practical experience in data analysis. Lectures and labs are the same as BIOL 421, but with additional assignments and evaluation appropriate to graduate studies. Prerequisite: Consent of instructor. Credit cannot be obtained for both BIOL 421 and BIOL 521. Offered in alternate years.

3 units (fi 6)(EITHER, 3-0-3)

Familiarizes the student with the practical aspects of statistical design in biology, the analysis of experimental and survey data, and interpretation of statistical results. Lectures emphasize the rationale for choosing statistical tests and an understanding of their mathematical foundation and framework. Labs and assignments provide hands-on training in data analysis with the R programming language and in the interpretation of software outputs, and stress critical thinking and scientific communication. Lectures and labs are the same as BIOL 430, but with additional assignments and evaluations appropriate to graduate studies. Prerequisites: Consent of Department. Credit cannot be obtained for BIOL 530 and BIOL 430 or REN R 480.

3 units (fi 6)(SECOND, 3-0-3)

Principles of population ecology as they apply to plants and animals; population consequences of variation among individuals; habitat structure and population structure; habitat selection and foraging theory; life tables, demography, life history patterns; population dynamics; interactions among organisms (predation, competition, mutualism, parasites/disease); harvesting; and population regulation. Highly quantitative content. Prerequisites: BIOL 208, 330; any one of MATH 113, 114, 115, 120, 125 or SCI 100; STAT 151 or SCI 151. Graduate students are evaluated with assessments appropriate to graduate studies.Credit may not be obtained for both BIOL 431 and BIOL 531.

3 units (fi 6)(EITHER, 0-3S-0)

An introduction to the broad field of Chemical Ecology through survey, discussion and analysis of current and historical literature. Topics include a wide array of chemically-mediated ecological interactions in a variety of taxa. Studies that analyze the importance of the use of chemical signals for habitat selection, resource acquisition, reproduction, defense and social interactions are discussed. Students research topics in Chemical Ecology and present their findings in oral and written formats. Graduate students complete an additional assignment and evaluation appropriate to graduate studies. Prerequisite: consent of instructor. Credit cannot be obtained for both BIOL 434 and 534. Offered in alternate years.

3 units (fi 6)(SECOND, 0-3S-0)

The course will introduce students to theory and techniques employed in the analysis of physical, hydrological, chemical, and ecological properties of ecosystems using a watershed (catchment) approach. Focus will be on landscape approaches relating interactions or linkages between upland, wetland/riparian, and surface-water in the study of the natural ecohydrologic function and response to disturbance of watershed ecosystems. Emphasis will be placed on Boreal Alberta. Topics are covered through reading the literature and group discussions. Seminars are the same as for BIOL 440, but with additional assignments and evaluation appropriate to graduate studies. Prerequisite: consent of instructor. Credit cannot be obtained for both BIOL 440 and 540.

3 units (fi 6)(EITHER, 0-3S-0)

This course explores the intersecting biological, chemical, and geological processes and reactions governing the cycling of elements that control our environment. Course discussions will include consideration of the atmosphere, lithosphere, hydrosphere and biosphere, and will be framed by our understanding that elemental cycling on Earth is fundamentally altered by organisms. Coursework will incorporate current topics in anthropogenic alteration of the natural cycles critical for organismal and planetary function. Seminars are the same as for BIOL 442, but with additional assignments and evaluation appropriate to graduate studies. Prerequisite: consent of Instructor. Credit cannot be obtained for both BIOL 442 and 542.

3 units (fi 6)(SECOND, 0-0-6)

Critical discussion and use of techniques for characterizing macromolecules from prokaryotic and eukaryotic systems. This course provides the theoretical and hands-on experience required to use classic and cutting-edge technologies to characterize the properties of these macromolecules. Prerequisite: consent of instructor. Lectures, assignments and exams are the same as BIOL 343 with additional assignments and evaluation appropriate to graduate studies. Credit can only be obtained for one of BIOL 343 or 543 or MICRB 343 or 345.

3 units (fi 6)(FIRST, 0-3S-0)

Survey, discussion and evaluation of literature dealing with current advances and selected topics in animal and cell physiology. Credit may be obtained more than once. Discussions are the same as for BIOL 445, but with additional assignments and evaluation appropriate to graduate studies. Enrolment of students by consent of instructor. Offered in alternate years.

3 units (fi 6)(SECOND, 0-3S-1)

Formulation, analysis, parameterization, and validation of quantitative models for ecological processes. Applications include population dynamics, species interactions, movement, and spatial processes. Approaches include classical hypothesis testing, computer simulation, differential equations, individual-based models, least squares, likelihood, matrix equations, Markov processes, multiple working hypotheses, and stochastic processes. The lab covers computer simulation methods. Prerequisite: consent of Instructor. Offered in alternate years.

3 units (fi 6)(SECOND, 3-0-3)

Landscapes are holistic entities whose patterns influence ecological processes. Topics highlighted in this course include landscape components, morphology and dynamics; detecting spatial/temporal change in landscapes; issues of scales; movements of organisms, disturbances, and nutrients across landscape mosaics; and restoration, planning and management in a landscape context. Labs emphasize GIS applications to characterizing landscape patterns and heterogeneity in space and time, distributing and moving organisms across landscapes, and restoring or planning landscapes for conservation objectives. Lectures and labs are the same as for BIOL 471, but with an additional research project and evaluation appropriate to graduate studies. Prerequisite: consent of instructor. Credit cannot be obtained for both BIOL 471 and 571.

3 units (fi 6)(SECOND, 0-1S-6)

A laboratory course introducing students to current molecular biology techniques and associated analyses used to study population genetics, systematics, and evolutionary biology in natural populations. Students will develop microsatellite marker systems and use them to examine the genetic structure of a natural population. A comparative bioinformatic approach will be used to generate sequence data to investigate the use of single nucleotide polymorphisms in candidate gene analysis and in phylogenetic inference. Labs are the same as BIOL 392, but with additional assignments and evaluation appropriate to graduate studies. Prerequisite: consent of instructor, corequisite: BIOL 380. Credit cannot be obtained for both BIOL 392 and 592.

3 units (fi 6)(EITHER, 0-3S-0)

Covers specialized topics of current interest to graduate students in Biological Sciences. Consult the Department for details about current offerings. Prerequisite: consent of instructor. Credit for this course may be obtained more than once.

3 units (fi 6)(EITHER, 3-0-3)

Covers specialized topics of current interest to graduate students in Biological Sciences. Consult the Department for details about current offerings. Prerequisite: consent of instructor. Credit for this course may be obtained more than once.

3 units (fi 6)(EITHER, 0-1S-6)

Covers specialized topics of current interest to graduate students in Biological Sciences. Consult the Department for details about current offerings. Prerequisite: consent of instructor. Credit for this course may be obtained more than once.

3 units (fi 6)(EITHER, 0-3S-0)

Designed for new graduate students in environmental biology to foster critical thinking and discussion and to introduce them to issues of experimental design and analysis and different approaches to ecology. The course involves student discussion of papers, lectures by faculty members on their research, seminars by students and a written assignment. Prerequisite: consent of instructor. Preference will be given to students in Biological Sciences.

1 unit (fi 2)(EITHER, 0-1S-0)

Credit may be obtained more than once.

1 unit (fi 2)(EITHER, 0-2S-0)

This course will cover specialized topics of current interest to graduate students in Biological Sciences with an emphasis on learning new research skills. Prerequisite: consent of Instructor. Credit for this course may be obtained more than once.

1 unit (fi 2)(EITHER, 0-2S-0)

Credit may be obtained more than once.

1 unit (fi 2)(EITHER, 0-0-3)

A credit/no-credit course for graduate students who are mentoring undergraduates in a research course (BIOL 398, 490 and 498) under the supervision of an academic member of the Department of Biological Sciences. Mentorship includes activities such as in lab or field supervision, training, and help with reports and presentations. Consent of Department of Biological Sciences required. Can be taken in any year. Credit may be obtained more than once.

1 unit (fi 4)(TWO TERM, 0-0-3)

A credit/no-credit course for graduate students who are mentoring undergraduates in a research course (BIOL 399 and 499) under the supervision of an academic member of the Department of Biological Sciences. Mentorship includes activities such as in lab or field supervision, training, and help with reports and presentations. Consent of Department of Biological Sciences required. Can be taken in any year. Credit may be obtained more than once.

1 unit (fi 4)(TWO TERM, 0-0-3)

A credit/no-credit course for graduate students who are mentoring undergraduates in a research course (BIOL 399 and 499) under the supervision of an academic member of the Department of Biological Sciences. Mentorship includes activities such as in lab or field supervision, training, and help with reports and presentations. Consent of Department of Biological Sciences required. Can be taken in any year. Credit may be obtained more than once.

3 units (fi 6)(EITHER(FR), 3-0-3) Open Study: Open

Introduction à la structure et au fonctionnement de la cellule. Les principaux sujets étudiés comprennent les cellules procaryotes et eucaryotes, la bioénergétique, comment les cellules se reproduisent et comment l'information génétique est emmagasinée et utilisée à travers les processus de réplication de l'ADN, de transcription et de traduction. Préalable(s): Biologie 30 et Chimie 30. Note: BIOLE 107 n'est pas un préalable pour BIOLE 108.

3 units (fi 6)(EITHER(FR), 3-0-3) Open Study: Open

Examine les grandes lignées de la vie sur la Terre. Un survol des principes de l'évolution et de la classification, l'histoire de la vie et les adaptations clefs des procaryotes, protistes, eumycètes, végétaux et animaux. Les laboratoires examinent la diversité de formes et de fonctions biologiques, et introduisent l'étudiant à la collecte de données et à la rédaction scientifique. Préalable: Biologie 30. Note: BIOLE 107 n'est pas un préalable pour BIOLE 108.

3 units (fi 6)(EITHER(FR), 3-0-0) Open Study: Open

Une dissection structurale et fonctionnelle de la cellule eucaryote. Détection de molécules spécifiques au niveau ultrastructural; structure et fonction de la membrane plasmique; rôle du cytosquelette dans le transport intracellulaire, la mitose et la cytocinèse; le système endomembranaire, le ciblage des protéines, l'exocytose et l'endocytose; structure et fonction du noyau; contrôle du cycle cellulaire et cancer. Préalable(s): BIOLE 107 et un cours de CHIM de niveau 100, ou SCI 100. Note: Ce cours n'est pas accessible aux étudiants ayant ou postulant des crédits pour CELL 201.

3 units (fi 6)(EITHER(FR), 3-1S-3) Open Study: Open

Les principes chromosomiques et moléculaires de la transmission et du fonctionnement des gènes; la construction de cartes génétiques et physiques des gènes et des génomes; les protocoles utilisés pour isoler des gènes spécifiques. Seront aussi à l'étude les exemples de mécanismes régulateurs pour l'expression de matériel génétique chez les procaryotes et les eucaryotes. Préalable(s): BIOLE 107 ou SCI 100.

3 units (fi 6)(EITHER(FR), 3-0-3) Open Study: Open

L'écologie est l'étude scientifique des interactions entre les organismes et leur environnement selon une hiérarchie de niveaux d'organisation: les individus, les populations, les communautés et les écosystèmes. Destiné à donner à l'étudiant une vue générale des concepts de base en écologie, ce cours peut aussi servir de préparation à des cours plus avancés. Dans les laboratoires, l'accent sera sur le recueil, l'analyse et l'interprétation des données provenant d'expériences écologiques afin d'illustrer et compléter les notes du cours. Les exemples seront tirés d'une vaste étendue d'organismes et de systèmes. Préalable(s): BIOLE 108 ou SCI 100.

3 units (fi 6)(EITHER(FR), 3-0-0)

Survol des effets néfastes des agents chimiques et physiques sur les systèmes biologiques dans un contexte écologique. Ce cours permet de comprendre les effets biologiques et leur évaluation grâce à une approche multidisciplinaire ancrée dans les savoirs occidentaux et autochtones. Préalable(s) BIOLE 208, ZOOL 241, ou PHYSE 210, ou PHYSL 212 ou 214 et CHIM 164 ou 261; ou équivalent. Note: Ce cours n'est pas accessible aux étudiants ayant ou postulant des crédits pour BIOL 341.

Effective: 2026-09-01 BIOLE 341 - Écotoxicologie

3 units (fi 6)(EITHER(FR), 3-0-0)

Survol des effets néfastes des agents chimiques et physiques sur les systèmes biologiques dans un contexte écologique. Ce cours permet de comprendre les effets biologiques et leur évaluation grâce à une approche multidisciplinaire ancrée dans les savoirs occidentaux et autochtones. Préalable(s) : BIOLE 208; ZOOL 241 ou PHYSE 210 ou PHYSL 212 ou 214; et CHIM 164 ou 261; ou équivalent. Note: Ce cours n'est pas accessible aux personnes étudiantes ayant ou postulant à des crédits pour BIOL 341.

3 units (fi 6)(EITHER(FR), 3-1S-0) Open Study: Open

Application de la biologie moléculaire à l'étude de la systématique, de la structure des populations naturelles, des systèmes d'accouplement et de la criminalistique. Les sujets discutés incluent les techniques de détection de la variation génétique des populations naturelles, l'analyse phylogénétique de données moléculaires, les modèles mathématiques de la structure des populations, l'analyse de paternité et les empreintes génétiques. Préalable: BIOLE 207. BIOLE 221 ou équivalent est recommandé.

3 units (fi 6)(EITHER(FR), 0-0-6)

Recherche dirigée sous la supervision d'un membre du personnel académique qui effectue des recherches dans le domaine des sciences biologiques. Les résultatsde la recherche seront présentés sous la forme d'un rapport écrit. Préalable(s): Un cours de niveau 200 en biologie ou en biochimie et l'approbation du superviseur de recherche. Note: L'accès à ce cours peut être limité par la disponibilité d'un superviseur de recherché.

3 units (fi 12)(2 TERM(FR), 0-0-6)

Recherche dirigée sous la supervision d'un membre du personnel académique qui effectue des recherches dans le domaine des sciences biologiques. Les résultats de la recherche seront présentés sous la forme d'un rapport écrit. Préalable(s): Un cours de niveau 200 en biologie ou en biochimie et l'approbation du superviseur de recherche. Note: L'accès à ce cours peut être limité par la disponibilité d'un superviseur de recherche.

3 units (fi 12)(2 TERM(FR), 0-0-6)

Recherche dirigée sous la supervision d'un membre du personnel académique qui effectue des recherches dans le domaine des sciences biologiques. Les résultats de la recherche seront présentés sous la forme d'un rapport écrit. Préalable(s): Un cours de niveau 200 en biologie ou en biochimie et l'approbation du superviseur de recherche. Note: L'accès à ce cours peut être limité par la disponibilité d'un superviseur de recherche.

3 units (fi 6)(EITHER(FR), 0-0-6)

L'inscription dépendra d'une entente préalable entre l'étudiant et un professeur qui serait prêt à superviser le projet. Des crédits peuvent être obtenus plus d'une fois pour ce cours. Préalable(s): 3 crédits de niveau 300 en sciences biologiques et l'approbation du Vice-doyen aux affaires académiques. Note: L'accès à ce cours peut être limité par la disponibilité d'un superviseur de recherche.

3 units (fi 6)(EITHER(FR), 0-0-6)

Recherche dirigée dans le laboratoire d'un membre du personnel académique en biologie. Des crédits peuvent être obtenus plus d'une fois pour ce cours. Préalable(s): 3 crédits de niveau 300 en sciences biologiques et l'approbation du superviseur de recherche. Note: L'accès à ce cours peut être limité par la disponibilité d'un superviseur de recherche.

3 units (fi 12)(2 TERM(FR), 0-0-6)

Recherche dirigée dans le laboratoire d'un membre du personnel académique en biologie. La complétion de ce projet requiert une présentation orale et un rapport écrit sur le projet de recherche. Préalable(s): 3 crédits de niveau 300 en sciences biologiques et l'approbation du superviseur de recherche. Note: L'accès à ce cours peut être limité par la disponibilité d'un superviseur de recherche.

3 units (fi 12)(2 TERM(FR), 0-0-6)

Recherche dirigée dans le laboratoire d'un membre du personnel académique en biologie. La complétion de ce projet requiert une présentation orale et un rapport écrit sur le projet de recherche. Préalable(s): 3 crédits de niveau 300 en sciences biologiques et l'approbation du superviseur de recherche. Note: L'accès à ce cours peut être limité par la disponibilité d'un superviseur de recherche.

3 units (fi 6)(FIRST, 3-0-0) Open Study: Open

Physical principles important to the operation of biological systems. Biological applications of free energy, entropy, random walks, and diffusion; dynamics at low Reynolds number; cooperativity and 2-state systems; structural self-assembly; kinetic modeling; molecular motors and enzymes; membranes and potentials; genetic networks; sequences and evolution. Prerequisites: MATH 100/114/117/134/144, PHYS 124/144 or EN PH131. PHYS 126/130/146 recommended.

3 units (fi 6)(SECOND, 3-0-0) Open Study: Open

Physical properties of biological macromolecules and macromolecular assemblies; biopolymer folding; ligand binding and allostery; lipid membranes; cellular electricity and nerve conduction; models of molecular motors; stochasticity in biology; numerical and experimental techniques in biophysics; synthetic biology. Prerequisites: MATH 209 or 215 or 315 or 317 or MA PH 351, MATH 201/334/336 or MA PH 251, BIOPH 201, PHYS 234, PHYS 230/281, PHYS 310.

3 units (fi 6)(SECOND, 3-0-0)

Physical properties of biological macromolecules and macromolecular assemblies; biopolymer folding; ligand binding and allostery; lipid membranes; cellular electricity and nerve conduction; models of molecular motors; stochasticity in biology; numerical and experimental techniques in biophysics; synthetic biology. Prerequisites: Consent of Instructor.

3 units (fi 6)(FIRST, 3-0-0)

An introduction to the fundamental levels of organization of the human body highlighted in engineering terms. The first half of the course will consider the chemical, cellular, and tissue levels of organization. The second half of the course will be devoted to bone, joints, muscle, and neural tissue. Guest lectures will include engineers and medical scientists to discuss the relationship between recent advances in biomedical engineering and the underlying anatomy and physiology. This course is intended for students in the Faculty of Engineering. Students from other faculties must obtain the consent of the Department of Biomedical Engineering. Credit may be obtained for only BME 210 or 320.

3 units (fi 6)(SECOND, 3-0-0)

An introduction to the organization of the human body at the level of the anatomical systems highlighted in engineering terms. Lectures will be devoted to the circulatory, respiratory, digestive, urinary, nervous and endocrine systems, and fluid, electrolyte and acid-base homeostasis. Guest lectures will include engineers and medical scientists to discuss the relationship between recent advances in biomedical engineering and the underlying anatomy and physiology. This course is intended for students in the Faculty of Engineering. Students from other faculties must obtain the consent of the Department of Biomedical Engineering. Credit may be obtained for only BME 211 or 321. Prerequisite: BME 320 or consent of Instructor.

3 units (fi 8)(EITHER, 3-0-0)

An introduction to design and development of bioinformatics algorithms and their applications in bioinformatics. Topics may include algorithms for sequence comparison/alignment, large-scale biological database search, evolutionary tree reconstruction, and identification of important features in nucleic acid and protein sequences and underlying computational techniques.

3 units (fi 6)(FIRST, 3-0-0)

Neuroimaging has developed rapidly in recent years, and has had a profound effect on how we understand the human brain. This advanced course is aimed to provide graduate students and senior undergraduate students a comprehensive overview of the neuroimaging techniques (structural and functional magnetic resonance imaging (MRI), diffusion tensor imaging (DTI), MRI spectroscopy (MRS) etc) currently used in neuroscience research. In addition, we will discuss how neuroimaging methods can advance our understanding of healthy brain function and neuropsychiatric disorders. Prerequisite: Consent of Instructor.

3 units (fi 6)(FIRST, 3-1S-0)

This course will give an overview of the stem cell biology and biomedical applications. Topics will include biological aspects of stem cells, environmental factors and signals that are implicated in regulating stem cell fate, the practical use of stem cells for tissue engineering and cellular therapies. The course will highlight techniques for engineering of stem cells and their micro-environments. The ethical, legal, and regulatory issues that accompany current and emerging stem cell engineering applications will be also discussed. This course is designed for upper undergraduates and graduate students with a strong interest in stem cell biology and stem cell engineering, and the desire to actively contribute to discussions in the class. Pre-requisites: BME 320 or consent of instructor.

3 units (fi 6)(SECOND, 3-0-0) Open Study: Open

Introduction to basic physical and technological aspects of medical imaging. Emphasis on computed transmission and emission tomography, magnetic resonance, and ultrasound imaging. These methods are developed and contrasted in terms of how imaging information is generated, detected, and processed and how different hardware configurations and other factors limit image quality. Relative diagnostic potential of the imaging methods is also discussed in relation to future prospects of each method.

3 units (fi 6)(SECOND, 3-0-0)

An advanced course for graduate students in Neuroscience and Biomedical Engineering that covers the cellular and systems level changes in sensorimotor and pain pathways in response to motor training and/or trauma to the nervous system. A background on experimental techniques and mechanisms of neuronal plasticity from key studies in cortical, spinal and dorsal horn systems will be provided. Students are expected to write and present on current topics in the field of motor and pain neuroplasticity. Students should have a basic background in neurophysiology. Prerequisites: PMCOL 371 and PHYSL 372 or equivalents or consent of instructor.

3 units (fi 6)(EITHER, 3-0-0)

Individual sections covering such topics as signal processing and rehabilitation engineering. Prerequisite: consent of Instructor.

3 units (fi 6)(SECOND, 3-1S-0) Open Study: Open

Introduction to rehabilitation techniques for assisting individuals with physical disabilities to reach, stand and walk. Biomechanics of intact and pathological movements and the use of assistive devices such as exoskeletal orthotics, neuroprosthetic devices and locomotor training are emphasized. Students are exposed to the concepts of biomechanical modeling, motion analysis, electrical stimulation, control systems, neuroregeneration, and pharmacology. Prerequisite: BME 320 and 321 or consent of Instructor.

3 units (fi 6)(FIRST, 3-0-0)

Designed for graduate and advanced undergraduate students requiring a thorough grounding in the fundamentals of imaging by means of nuclear magnetic resonance, NMR. Topics include the principles of NMR as applied to imaging, image processing, imaging techniques for achieving specific types of contrast, image artefacts, and typical applications. Prerequisite: Consent of instructor.

3 units (fi 6)(EITHER, 3-0-0)

Mechanisms of interfacing with and modulating the central nervous system that define the characteristics of bionic devices. Topics include invasive and non-invasive neural interfaces and using neuromodulation as a tool for restoring sensory and motor functions.